ArticlePlant physiology2020
Structure and Function of the Cytochrome P450 Monooxygenase Cinnamate 4-hydroxylase from
Article in Plant physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 75 citations in OpenAlex.
- Cloning and functional characterization of a cinnamate 4-hydroxylase (SmC4H) from the lycophyte Selaginella moellendorffii.Protoplasma · 2026Article
- Cytochrome P450 enzymes in the phenylpropanoid pathway: CYP73 and CYP98 candidate genes in Chara braunii, Anthoceros agrestis, Marchantia polymorpha and Physcomitrium patens.The Plant journal : for cell and molecular biology · 2026Article
- Catalytic Promiscuity Underpins Metabolic Resistance to Auxinic Herbicides inJournal of agricultural and food chemistry · 2026Article
- Integrated transcriptomic and metabolomic analyses reveal the mechanism of shoot growth in grafted Camellia oleifera seedlings.BMC genomics · 2026Article
- Complex Roles of Insect Cytochrome P450s in Chemical Adaptation.International journal of biological sciences · 2026Review
- Article
- Study on the dynamics of fruits color related genes and metabolites during the fruit development of Zanthoxylum bungeanum 'Hanyuan'.BMC plant biology · 2025Article
- CYP98A monooxygenases: a key enzyme family in plant phenolic compound biosynthesis.Horticulture research · 2025Article
- Unraveling the trisubstrate-triproduct reaction mechanisms of wine grape VvCYP76F14 to improve wine bouquet.Food chemistry · 2025Article
- Regulatory mechanisms and biosynthesis of chlorogenic acid inFrontiers in plant science · 2025Review
- Biochemical evaluation of molecular parts for flavonoid production using plant synthetic biology.Frontiers in plant science · 2025Review
- Exploring the mechanism of seed shattering in Psathyrostachys juncea through histological analysis and comparative transcriptomics.BMC plant biology · 2024Article
- D299T Mutation in CYP76F14 Led to a Decrease in Wine Bouquet Precursor Production in Wine Grape.Genes · 2024Article
- Comprehensive Review on Plant Cytochrome P450 Evolution: Copy Number, Diversity, and Motif Analysis From Chlorophyta to Dicotyledoneae.Genome biology and evolution · 2024Review
- An ancient role for CYP73 monooxygenases in phenylpropanoid biosynthesis and embryophyte development.The EMBO journal · 2024Article
- Versatile CYP98A enzymes catalyse meta-hydroxylation reveals diversity of salvianolic acids biosynthesis.Plant biotechnology journal · 2024Article
- Site-Directed Mutagenesis of VvCYP76F14 (Cytochrome P450) Unveils Its Potential for Selection in Wine Grape Varieties Linked to the Development of Wine Bouquet.Journal of agricultural and food chemistry · 2024Article
- Revealing the dynamic changes of metabolites and molecular mechanisms of chlorogenic acid accumulation during the leaf development ofFrontiers in plant science · 2024Article
- Comparative Analysis of Cd Uptake and Tolerance in Two Mangrove Species (Plants (Basel, Switzerland) · 2023Article
- Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cinnamate 4-hydroxylase (C4H; CYP73A) is a cytochrome P450 monooxygenase associated externally with the endoplasmic reticulum of plant cells. The enzyme uses NADPH-cytochrome P450 reductase as a donor of electrons and hydroxylates cinnamic acid to form 4-coumaric acid in phenylpropanoid metabolism. In order to better understand the structure and function of this unique class of plant P450 enzymes, we have characterized the enzyme C4H1 from lignifying tissues of sorghum (
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