ArticleKidney international2020
Syndecan-4: major player or innocent bystander of the endothelial glycocalyx?
Article in Kidney international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The Endothelial Glycocalyx: The First Line of Defense in the Prevention and Treatment of Kidney Diseases.Kidney medicine · 2025Review
- Endothelial CXCR2 deficiency attenuates renal inflammation and glycocalyx shedding through NF-κB signaling in diabetic kidney disease.Cell communication and signaling : CCS · 2024Article
- Early diabetic kidney disease: Focus on the glycocalyx.World journal of diabetes · 2023Review
Corrections and comments
- Comment on
Authors and funding
1 author.
Funding
Abstract
Glycocalyces are the pericellular coat of glycoproteins, glycolipids, and proteoglycans. Yet the exploration of glycocalyx function is still ongoing because of the availability of investigative tools capable of discerning the function of one component without inflicting collateral changes in the organization/function of other constituents. The current report by Ramnath et al. explores the function of one family of molecules, the syndecans, as potential regulators of endothelial cell glycocalyx thickness in normal and diabetic glomeruli.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.