Evidence map›Paper›PMID 32331468›Full record

ArticleMicromachines2020

Scalable Parallel Manipulation of Single Cells Using Micronozzle Array Integrated with Bidirectional Electrokinetic Pumps.

Moeto Nagai, Keita Kato, Satoshi Soga, Tuhin Subhra Santra, Takayuki Shibata

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Moeto NagaiDepartment of Mechanical Engineering, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan.
Keita KatoDepartment of Mechanical Engineering, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan.
Satoshi SogaDepartment of Mechanical Engineering, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan.
Tuhin Subhra SantraDepartment of Engineering Design, Indian Institute of Technology Madras, Tamil Nadu 600036, India.
Takayuki ShibataDepartment of Mechanical Engineering, Toyohashi University of Technology, Toyohashi, Aichi 441-8580, Japan.

Funding

DBT-Wellcome Trust India Alliance IA/E/16/1/503062Japan Science and Technology Agency VP30218089109Japan Society for the Promotion of Science 25820087, 15K13910,16H06074
6 · The paper itself

Abstract

High throughput reconstruction of in vivo cellular environments allows for efficient investigation of cellular functions. If one-side-open multi-channel microdevices are integrated with micropumps, the devices will achieve higher throughput in the manipulation of single cells while maintaining flexibility and open accessibility. This paper reports on the integration of a polydimethylsiloxane (PDMS) micronozzle array and bidirectional electrokinetic pumps driven by DC-biased AC voltages. Pt/Ti and indium tin oxide (ITO) electrodes were used to study the effect of DC bias and peak-to-peak voltage and electrodes in a low conductivity isotonic solution. The flow was bidirectionally controlled by changing the DC bias. A pump integrated with a micronozzle array was used to transport single HeLa cells into nozzle holes. The application of DC-biased AC voltage (100 kHz, 10 V

Indexed as

bidirectional electrokinetic pumpDC biased AC electrokinetic flowmicronozzle-arrayparallel cell manipulation

Identifiers

PMID32331468
PMCPMC7231381

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.