Evidence map›Paper›PMID 32331447›Full record

ArticleInternational journal of molecular sciences2020

Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors.

Özlen Güzel-Akdemir, Simone Carradori, Rossella Grande, Kübra Demir-Yazıcı, Andrea Angeli, Claudiu T Supuran, Atilla Akdemir

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Carbonic Anhydrases: A Superfamily of Ubiquitous Enzymes.International journal of molecular sciences · 2023
    Article
  2. Biological investigation ofJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  3. Azole-Based Compounds That Are Active againstAntibiotics (Basel, Switzerland) · 2022
    Article
  4. Emerging Antifungal Targets and Strategies.International journal of molecular sciences · 2022
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Özlen Güzel-AkdemirIstanbul University, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 34116 Istanbul, Turkey.ORCID 0000-0003-3680-1945
Simone CarradoriDipartimento di Farmacia, "G. d'Annunzio" University of Chieti-Pescara, Via dei vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-8698-9440
Rossella GrandeDipartimento di Farmacia, "G. d'Annunzio" University of Chieti-Pescara, Via dei vestini 31, 66100 Chieti, Italy.ORCID 0000-0002-8432-6889
Kübra Demir-YazıcıIstanbul University, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 34116 Istanbul, Turkey.
Andrea AngeliNeurofarba Department, Section of Pharmaceutical and Nutraceutical Sciences, Università degli Studi di Firenze, Via U. Schiff 6, 50019 Sesto Fiorentino (Florence), Italy.ORCID 0000-0002-1470-7192
Claudiu T SupuranNeurofarba Department, Section of Pharmaceutical and Nutraceutical Sciences, Università degli Studi di Firenze, Via U. Schiff 6, 50019 Sesto Fiorentino (Florence), Italy.ORCID 0000-0003-4262-0323
Atilla AkdemirBezmialem Vakif University, Computer-aided drug discovery laboratory, Department of Pharmacology, Faculty of Pharmacy, 34093 Istanbul, Turkey.ORCID 0000-0001-8416-0471

Funding

Research Fund of the Istanbul University (Project Number BEK 24737). BEK 24737
6 · The paper itself

Abstract

In our efforts to find new and selective thiazolidinone-based anti-

Indexed as

Drug DevelopmentAntifungal AgentsBinding SitesCandidaCarbonic Anhydrase InhibitorsCatalytic DomainHumansMicrobial Sensitivity TestsMolecular ConformationMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructureProtein BindingStructure-Activity RelationshipAntifungal AgentsCarbonic Anhydrase Inhibitors4-thiazolidinonesantifungal activitycarbonic anhydrasesCgNce103CYP51a1lanosterol 14α-demethylasemolecular modelling studies

Identifiers

PMID32331447
PMCPMC7215574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.