ReviewBiomolecules2020
High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases.
Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- High-Density Lipoprotein Cholesterol Levels and Risk of Age-Related Macular Degeneration.Investigative ophthalmology & visual science · 2026Article
- Association of High-Density Lipoprotein Cholesterol with Macular Structure in Nonglaucomatous Individuals.Ophthalmology science · 2026Article
- Association rule analysis of physical activity and multimorbidity in middle-aged Korean adults with diabetes: an evidence to promote active lifestyles.BMC public health · 2026Article
- Integrating Mendelian randomization and multi-transcriptomic analyses to unveil the genetic association risk of regulatory T cell-mediated free cholesterol and gastric cancer.Discover oncology · 2025Article
- The association between the C-reactive protein-to-albumin-to-lymphocyte index and retinopathy: insights from a population-based study.Frontiers in nutrition · 2025Article
- Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and age-related macular degeneration: insights from two observational studies.Frontiers in medicine · 2025Article
- Association between dyslipidemia and neovascular age-related macular degeneration: a case-control study.International journal of clinical and experimental pathology · 2025Article
- Candidate SNP Markers Significantly Altering the Affinity of the TATA-Binding Protein for the Promoters of Human Genes Associated with Primary Open-Angle Glaucoma.International journal of molecular sciences · 2024Article
- Serum lipid and lipoprotein profiles and their association with intraocular pressure in primary open-angle glaucoma: an observational cross-sectional study in the Chinese population.Lipids in health and disease · 2024Observational
- Risk Factors of Age-Related Macular Degeneration in a Population-Based Study: Results from SHIP-TREND-1 (Study of Health in Pomerania-TREND-1).Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Distinct and Overlapping Metabolites Associated with Visual Impairment and Cognitive Impairment.Journal of Alzheimer's disease reports · 2024Article
- The Association between Cholesterol Levels and Severity of Normal Tension Glaucoma.Molecular vision · 2023Article
- Cholesterol and oxysterols in retinal neuron-glia interactions: relevance for glaucoma.Frontiers in ophthalmology · 2023Review
- Relationships between Lipid-Related Metabolites and Age-Related Macular Degeneration Vary with Complement Genotype.Ophthalmology science · 2022Article
- Lipid profile and future risk of exudative age-related macular degeneration development: a nationwide cohort study from South Korea.Scientific reports · 2022Article
- Elevated Plasma Levels of C1qTNF1 Protein in Patients with Age-Related Macular Degeneration and Glucose Disturbances.Journal of clinical medicine · 2022Article
- Artificial Intelligence Analysis of Biofluid Markers in Age-Related Macular Degeneration: A Systematic Review.Clinical ophthalmology (Auckland, N.Z.) · 2022Review
- Molecular Patterns of Extreme and Persistent Cholesterol Efflux Capacity.Arteriosclerosis, thrombosis, and vascular biology · 2021Article
- Epistatic interactions of genetic loci associated with age-related macular degeneration.Scientific reports · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is limited understanding of the specific role of high-density lipoprotein cholesterol (HDL-C) in the development of various age-related ocular diseases, despite it being a common measurable biomarker in lipid profiles. This literature review summarizes current knowledge of the role of HDL-C, if any, in pathogenesis and progression of four age-related ocular diseases, namely age-related macular degeneration (AMD), age-related cataract, glaucoma, and diabetic retinopathy (DR), and will primarily discuss epidemiological and genetic evidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.