Evidence map›Paper›PMID 32331347›Full record

ReviewInternational journal of molecular sciences2020

Crosstalk of lncRNA and Cellular Metabolism and Their Regulatory Mechanism in Cancer.

Yang-Hsiang Lin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.

  1. Pooled it
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  15. Article
  16. The role of LncRNA-mediated autophagy in cancer progression.Frontiers in cell and developmental biology · 2024
    Review
  17. Review
  18. Silencing of the long non-coding RNAOncology research · 2024
    Article
  19. Article
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Yang-Hsiang LinLiver Research Center, Chang Gung Memorial Hospital, Linkou, Taoyuan 333, Taiwan.ORCID 0000-0003-4295-6062
Chang Gung University · TW

Funding

Chang Gung Memorial Hospital CMRPG3H0721, CMRPG3H0722, CMRPG3H0723Chang Gung Memorial Hospital NZRPG3G0171, NZRPG3G0172, NZRPG3G0173, NMRPG3H0561, NRRPG3J0141Ministry of science and technology, Taiwan 106-2321-B-182A-004-MY3, 107-2320-B-182A-028-, 108-2320-B-182A-004-
6 · The paper itself

Abstract

The imbalanced regulation of metabolic homeostasis and energy production is highly associated with inflammation, tumor growth, metastasis and cancer progression. Both glycolysis and oxidative phosphorylation maintain metabolic homeostasis and energy production in cells. Long noncoding RNAs (lncRNAs) are a class of non-protein-coding transcripts longer than 200 nucleotides. Furthermore, lncRNAs can function as either tumor suppressors or oncogenes in cancer. Dysregulated lncRNAs reportedly regulate cancer hallmarks such as tumor growth, metabolism and metastasis. Accordingly, uncovering the interaction between lncRNAs and cellular metabolism has become a necessity when attempting to identify effective therapeutic and preventive strategies in cancer progression. This review summarizes important knowledge of the actions of known lncRNAs-mediated cancer metabolism.

Indexed as

Energy MetabolismGene Expression Regulation, NeoplasticSignal TransductionAnimalsGene Expression Regulation, EnzymologicGlycolysisHumansMitochondriaNeoplasmsOxidative PhosphorylationOxidative StressRNA, Long NoncodingRNA, Long NoncodingcancerglycolysislncRNAmitochondriatherapeutic target

Identifiers

PMID32331347
PMCPMC7215767
OpenAlexW3018335552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.