Evidence map›Paper›PMID 32331331›Full record

ReviewJournal of clinical medicine2020

Long Non-Coding RNAs in Biliary Tract Cancer-An Up-to-Date Review.

Dino Bekric, Daniel Neureiter, Markus Ritter, Martin Jakab, Martin Gaisberger, Martin Pichler, Tobias Kiesslich, Christian Mayr

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dino BekricInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0003-3928-519X
Daniel NeureiterInstitute of Pathology, Paracelsus Medical University/Salzburger Landeskliniken (SALK), 5020 Salzburg, Austria.
Markus RitterInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0001-7346-7750
Martin JakabInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0003-2110-5090
Martin GaisbergerInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0002-3757-5612
Martin PichlerResearch Unit of Non-Coding RNAs and Genome Editing, Division of Clinical Oncology, Department of Medicine, Comprehensive Cancer Center Graz, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-8701-9462
Tobias KiesslichInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.
Christian MayrInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.
Paracelsus Medical University · ATMedical University of Graz · AT

Funding

Österreichische Krebshilfe Salzburg 2018
6 · The paper itself

Abstract

The term long non-coding RNA (lncRNA) describes non protein-coding transcripts with a length greater than 200 base pairs. The ongoing discovery, characterization and functional categorization of lncRNAs has led to a better understanding of the involvement of lncRNAs in diverse biological and pathological processes including cancer. Aberrant expression of specific lncRNA species was demonstrated in various cancer types and associated with unfavorable clinical characteristics. Recent studies suggest that lncRNAs are also involved in the development and progression of biliary tract cancer, a rare disease with high mortality and limited therapeutic options. In this review, we summarize current findings regarding the manifold roles of lncRNAs in biliary tract cancer and give an overview of the clinical and molecular consequences of aberrant lncRNA expression as well as of underlying regulatory functions of selected lncRNA species in the context of biliary tract cancer.

Indexed as

biliary tract cancercholangiocarcinomaEZH2gallbladder cancerlncRNAlong-noncoding RNA

Identifiers

PMID32331331
PMCPMC7231154
OpenAlexW3018824062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.