Evidence map›Paper›PMID 32331302›Full record

ArticleInternational journal of molecular sciences2020

Amino-Functionalized Nitrogen-Doped Graphene-Quantum-Dot-Based Nanomaterials with Nitrogen and Amino-Functionalized Group Content Dependence for Highly Efficient Two-Photon Bioimaging.

Wen-Shuo Kuo, Chia-Yuan Chang, Keng-Shiang Huang, Jui-Chang Liu, Yu-Ting Shao, Chih-Hui Yang, Ping-Ching Wu

Abstract read
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Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wen-Shuo KuoSchool of Chemistry and Materials Science, Nanjing University of Information Science and Technology, Nanjing 210044, China.
Chia-Yuan ChangDepartment of Mechanical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Keng-Shiang HuangThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung 840, Taiwan.ORCID 0000-0002-7751-0223
Jui-Chang LiuAllergy & Clinical Immunology Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.
Yu-Ting ShaoAllergy & Clinical Immunology Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.
Chih-Hui YangDepartment of Biological Science and Technology, I-Shou University, Kaohsiung 840, Taiwan.
Ping-Ching WuDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.

Funding

Ministry of Science and Technology, Taiwan MOST 108-2314-B-006-053-
6 · The paper itself

Abstract

We fabricated nanomaterials comprising amino-functionalized and nitrogen-doped graphene quantum dots (amino-N-GQDs) and investigated their photostability and intrinsic luminescence in the near-infrared spectrum to determine their suitability as contrast agents in two-photon imaging (TPI). We observed that amino-N-GQDs with a higher amount of bonded nitrogen and amino-functionalized groups (6.2%) exhibited superior two-photon properties to those with a lower amount of such nitrogen and groups (4.9%). These materials were conjugated with polymers containing sulfur (polystyrene sulfonate, PSS) and nitrogen atoms (polyethylenimine, PEI), forming amino-N-GQD-PSS-PEI specimens (amino-N-GQD-polymers). The polymers exhibited a high quantum yield, remarkable stability, and notable two-photon properties and generated no reactive oxygen species, rendering them excellent two-photon contrast agents for bioimaging. An antiepidermal growth factor receptor (Ab

Indexed as

Molecular ImagingPhotonsQuantum DotsCell LineGraphiteHumansImaging, Three-DimensionalNanostructuresNitrogenPolymersSpectrum AnalysisX-Ray DiffractionGraphiteNitrogenPolymersgraphene quantum dotnoninvasive three-dimensional imagingtwo-photon autofluorescencetwo-photon photopropertiesultralow two-photon excitation power

Identifiers

PMID32331302
PMCPMC7215431

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.