Evidence map›Paper›PMID 32331298›Full record

ArticleInternational journal of environmental research and public health2020

Environmental and Occupational Risk Factors of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study.

Tommaso Filippini, Marina Tesauro, Maria Fiore, Carlotta Malagoli, Michela Consonni, Federica Violi, Laura Iacuzio, Elisa Arcolin, Gea Oliveri Conti, Antonio Cristaldi and 9 more

Registry-linked trialAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07233148 (Healing ALS Registry Observational Study), which is not on this map. Cited by 35 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07233148 recruitingnot on this mapstarted 2026, after this paper: background citation

Healing ALS Registry Observational Study (HAROS)

Typeobservational_patient_registrySponsorHealing Advocates Registry and MinistryRan2026 to 2036Enrolled1,000ConditionsAmyotrophic Lateral Sclerosis (ALS), Motor Neuron Disease (MND), Primary Lateral Sclerosis (PLS)ArmsEducation about treatment options, Dietary Supplements: Vitamins, Minerals, Herbs, etc., Meditation, Prayer, Talk Therapy, Affirmations, Journaling, etc., Diet, various diets will be observed, Exercise, physical therapy, occupational therapy, speech therapy, sauna, EMS, massage and other therapies
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Environmental toxins in neurodegeneration - a narrative review.Neurological research and practice · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Military Service Roles and ALS Among Veterans: A Matched Case-Control Study.Annals of clinical and translational neurology · 2025
    Article
  13. Article
  14. Article
  15. Atrial Fibrillation and Other Cardiovascular Factors and the Risk of Dementia: An Italian Case-Control Study.International journal of environmental research and public health · 2024
    Article
  16. Review
  17. Review
  18. Occupational history associates with ALS survival and onset segment.Amyotrophic lateral sclerosis & frontotemporal degeneration · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Tommaso FilippiniCREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0003-2100-0344
Marina TesauroDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.ORCID 0000-0001-5542-5119
Maria FioreDepartment of Medical, Surgical Sciences and Advanced Technologies "G. F. Ingrassia", Catania University, 95123 Catania, Italy.
Carlotta MalagoliCREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Michela ConsonniDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-5078-0135
Federica VioliCREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Laura IacuzioCREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Elisa ArcolinCREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Gea Oliveri ContiDepartment of Medical, Surgical Sciences and Advanced Technologies "G. F. Ingrassia", Catania University, 95123 Catania, Italy.ORCID 0000-0003-1857-8612
Antonio CristaldiDepartment of Medical, Surgical Sciences and Advanced Technologies "G. F. Ingrassia", Catania University, 95123 Catania, Italy.
Pietro ZuccarelloDepartment of Medical, Surgical Sciences and Advanced Technologies "G. F. Ingrassia", Catania University, 95123 Catania, Italy.
Elisabetta ZucchiNeurology Unit, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Letizia MazziniALS Centre Department of Neurology, 'Maggiore della Carità' University Hospital, 28100 Novara, Italy.
Fabrizio PisanoNeurological Rehabilitation Division, Policlinico San Marco di Zingonia, 24046 Zingonia (BG), Italy.
Ileana GagliardiALS Centre Department of Neurology, 'Maggiore della Carità' University Hospital, 28100 Novara, Italy.
Francesco PattiDepartment of Medical, Surgical Sciences and Advanced Technologies "G. F. Ingrassia", Catania University, 95123 Catania, Italy.ORCID 0000-0002-6923-0846
Jessica MandrioliNeurology Unit, Department of Neuroscience, S. Agostino Estense Hospital, Azienda Ospedaliero Universitaria di Modena, 41126 Modena, Italy.ORCID 0000-0002-9244-9782
Margherita FerranteDepartment of Medical, Surgical Sciences and Advanced Technologies "G. F. Ingrassia", Catania University, 95123 Catania, Italy.ORCID 0000-0001-7596-2464
Marco VincetiCREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-0551-2473

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amyotrophic Lateral SclerosisNeurodegenerative DiseasesOccupational ExposureAgedCase-Control StudiesFemaleHumansItalyMaleMiddle AgedRisk Factorsamyotrophic lateral sclerosiscase-control studyenvironmental factorsoccupational factors

Identifiers

PMID32331298
PMCPMC7216189

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.