Evidence map›Paper›PMID 32331295›Full record

ReviewSensors (Basel, Switzerland)2020

Why Are Viscosity and Nonlinearity Bound to Make an Impact in Clinical Elastographic Diagnosis?

Guillermo Rus, Inas H Faris, Jorge Torres, Antonio Callejas, Juan Melchor

Open access · goldAbstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Guillermo RusUltrasonics Group (TEP-959), Department of Structural Mechanics, University of Granada, 18071 Granada, Spain.
Inas H FarisUltrasonics Group (TEP-959), Department of Structural Mechanics, University of Granada, 18071 Granada, Spain.
Jorge TorresUltrasonics Group (TEP-959), Department of Structural Mechanics, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-9488-6794
Antonio CallejasUltrasonics Group (TEP-959), Department of Structural Mechanics, University of Granada, 18071 Granada, Spain.
Juan MelchorBiomechanics Group (TEC-12), Instituto de Investigación Biosanitaria, ibs.GRANADA, 18012 Granada, Spain.
Universidad de Granada · ES

Funding

MECHANISMS OF ONSET &OFFSET OF RAPID STIMULANT EFFECTSK08DA000339 · NIDA · UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK · PI GENTRY, W BROOKS · 1998 to 2002
$527k
Instituto de Salud Carlos III .Juan de la Cierva Incorporación IJC2018-037167-IJunta de Andalucía IE2017-5537Junta de Andalucía PI-0107-2017Junta de Andalucía PIN-0030-2017Ministerio de Ciencia, Innovación y Universidades PRE2018-086085Ministerio de Educación, Cultura y Deporte DPI2014-51870-RMinisterio de Educación, Cultura y Deporte DPI2017-83859-RMinisterio de Educación, Cultura y Deporte EQC2018-004508-PMinisterio de Educación, Cultura y Deporte UNGR15-CE-3664Ministerio de Sanidad, Servicios Sociales e Igualdad DTS15/00093Ministerio de Sanidad, Servicios Sociales e Igualdad PI16/00339
6 · The paper itself

Abstract

The adoption of multiscale approaches by the biomechanical community has caused a major improvement in quality in the mechanical characterization of soft tissues. The recent developments in elastography techniques are enabling in vivo and non-invasive quantification of tissues' mechanical properties. Elastic changes in a tissue are associated with a broad spectrum of pathologies, which stems from the tissue microstructure, histology and biochemistry. This knowledge is combined with research evidence to provide a powerful diagnostic range of highly prevalent pathologies, from birth and labor disorders (prematurity, induction failures, etc.), to solid tumors (e.g., prostate, cervix, breast, melanoma) and liver fibrosis, just to name a few. This review aims to elucidate the potential of viscous and nonlinear elastic parameters as conceivable diagnostic mechanical biomarkers. First, by providing an insight into the classic role of soft tissue microstructure in linear elasticity; secondly, by understanding how viscosity and nonlinearity could enhance the current diagnosis in elastography; and finally, by compounding preliminary investigations of those elastography parameters within different technologies. In conclusion, evidence of the diagnostic capability of elastic parameters beyond linear stiffness is gaining momentum as a result of the technological and imaging developments in the field of biomechanics.

Indexed as

ViscosityBiomechanical PhenomenaElasticity Imaging TechniquesHumanselastographynonlinearitysoft tissueviscoelasticity

Identifiers

PMID32331295
PMCPMC7219338
OpenAlexW3018277779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.