Evidence map›Paper›PMID 32331263›Full record

ReviewInternational journal of molecular sciences2020

Cold Atmospheric Plasma: A Powerful Tool for Modern Medicine.

Dušan Braný, Dana Dvorská, Erika Halašová, Henrieta Škovierová

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 134 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 3 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05894096 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Air Cold Atmospheric Pressure Plasma Treatment for Acceleration of Venous Ulcer Healing

TypeinterventionalSponsorClinica Universidad de Navarra, Universidad de NavarraRan2023 to 2025Enrolled68ConditionsVenous Leg UlcerArmsCold Atmospheric Plasma Jet Treatment, Alginate Patch
NCT05924867 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Application of Plasma Activated Saline in Wound Treatment

TypeinterventionalSponsorFirst Affiliated Hospital Xi'an Jiaotong UniversityRan2023 to 2024Enrolled162ConditionsWound, Wound Infection, Wound HealArmsplasma activated saline, Routine nursing
3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 3 syntheses or guidelines pooled it, 326 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Cold Atmospheric Plasma in Wound Healing: Molecular Mechanism of Action.International journal of molecular sciences · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Electrochemical Detection of NO and CaPlasma chemistry and plasma processing · 2026
    Article
  19. Article
  20. Review

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dušan BranýBiomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Dana DvorskáBiomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Erika HalašováBiomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Henrieta ŠkovierováBiomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Comenius University Bratislava · SK

Funding

Agentúra na Podporu Výskumu a Vývoja APVV-15-0217Vedecká Grantová Agentúra MŠVVaŠ SR a SAV 1/0178/17
6 · The paper itself

Abstract

Cold atmospheric plasma use in clinical studies is mainly limited to the treatment of chronic wounds, but its application in a wide range of medical fields is now the goal of many analyses. It is therefore likely that its application spectrum will be expanded in the future. Cold atmospheric plasma has been shown to reduce microbial load without any known significant negative effects on healthy tissues, and this should enhance its possible application to any microbial infection site. It has also been shown to have anti-tumour effects. In addition, it acts proliferatively on stem cells and other cultivated cells, and the highly increased nitric oxide levels have a very important effect on this proliferation. Cold atmospheric plasma use may also have a beneficial effect on immunotherapy in cancer patients. Finally, it is possible that the use of plasma devices will not remain limited to surface structures, because current endeavours to develop sufficiently miniature microplasma devices could very likely lead to its application in subcutaneous and internal structures. This study summarises the available literature on cold plasma action mechanisms and analyses of its current in vivo and in vitro use, primarily in the fields of regenerative and dental medicine and oncology.

Indexed as

Cell ProliferationDental CareHumansPlasma GasesRegenerationRegenerative MedicineStem CellsWound HealingPlasma Gasescold atmospheric plasmaoncologyplasmaregenerative medicinewound healing

Identifiers

PMID32331263
PMCPMC7215620
OpenAlexW3018278469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.