Evidence map›Paper›PMID 32331251›Full record

ArticleInternational journal of molecular sciences2020

Beneficial Effects of Melatonin on Apolipoprotein-E Knockout Mice by Morphological and

Lorenzo Nardo, Rita Rezzani, Luca Facchetti, Gaia Favero, Caterina Franco, Yasser Gaber Abdelhafez, Ramsey Derek Badawi, Michele Guindani, Youngho Seo, Miguel Pampaloni

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Relation Between Reactive Oxygen Species Production and Transient Receptor Potential Vanilloid1 Expression in Human Skin During Aging.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2024
    Article
  3. Article
  4. Melatonin ameliorates PMJournal of pineal research · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Lorenzo NardoDepartment of Radiology, University of California, Davis, CA 97817, USA.
Rita RezzaniAnatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0002-7515-5846
Luca FacchettiDepartment of Radiology, University of Brescia, 25123 Brescia, Italy.
Gaia FaveroAnatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0001-6895-7106
Caterina FrancoAnatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Yasser Gaber AbdelhafezDepartment of Radiology, University of California, Davis, CA 97817, USA.ORCID 0000-0002-1989-3094
Ramsey Derek BadawiDepartment of Radiology, University of California, Davis, CA 97817, USA.
Michele GuindaniDepartment of Statistics, University of California, Irvine, CA 92697, USA.
Youngho SeoDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA.ORCID 0000-0001-5908-6636
Miguel PampaloniDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA.
University of Brescia · ITUniversity of California, Davis · USUniversity of California, San Francisco · USUniversity of California, Irvine · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura Marcu · 2002 to 2026
$84.9M
Targeted Imaging Agents Based on Synthetically Modified Viral CapsidsR21EB018055 · NIBIB · UNIVERSITY OF CALIFORNIA BERKELEY · PI FRANCIS, MATTHEW B · 2014 to 2015
$392k
NIH HHS R21EB018055Università degli Studi di Brescia ex-60%
6 · The paper itself

Abstract

Atherosclerosis represents one of the main risk factors for the development of cardiovascular diseases. Their etiologies have been studied in recent years in order to better define therapeutic targets for intervention and to identify diagnostic methods. Two different subtypes of macrophages, M1 and M2, have been described in physiological conditions. They can also be found in the atherosclerotic process, where they both have opposite roles in disease progression. Perivascular brown adipose tissue is also involved in inflammation and endothelial damage. In this work, we provide insights into the protective role of melatonin in the atherosclerotic process by morphological and

Indexed as

Fluorodeoxyglucose F18Molecular ImagingPositron Emission Tomography Computed TomographyAdipose Tissue, BrownAnimalsAortitisApolipoproteins EAtherosclerosisBiomarkersCytokinesDisease Models, AnimalFluorescent Antibody TechniqueHumansMacrophagesMelatoninMiceApolipoproteins EBiomarkersCytokinesFluorodeoxyglucose F18MelatoninRadiopharmaceuticalsatherosclerosismacrophage polarizationmelatoninmolecular imagingperivascular brown adipose tissuePET/CT

Identifiers

PMID32331251
PMCPMC7216051
OpenAlexW3017522405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.