Evidence map›Paper›PMID 32330948›Full record

ReviewHormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme2020

Developments in Primary Aldosteronism Subtyping Using Steroid Profiling.

Taweesak Wannachalee, Adina F Turcu

Open access · bronzeAbstract readReview
In one paragraph

Review in Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. 18-Oxocortisol: A journey.The Journal of steroid biochemistry and molecular biology · 2023
    Article
  5. Article
  6. Review
  7. Progress in Primary Aldosteronism 2019: New Players on the Block?Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Taweesak WannachaleeDivision of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-5439-6894
Adina F TurcuDivision of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-9831-6190
Siriraj Hospital · THUniversity of Michigan · US

Funding

The contemporary endocrinology of congenital adrenal hyperplasiaK08DK109116 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TURCU, ADINA F · 2016 to 2020
$832k
2019087 The Doris Duke Charitable FoundationDoris Duke Charitable Foundation 2019087K08DK109116 The NIDDKNIDDK NIH HHS K08 DK109116
6 · The paper itself

Abstract

Adrenal venous sampling is the standard of care for identifying patients with unilateral primary aldosteronism, which is often caused by an aldosterone producing adenoma and can be cured with surgery. The numerous limitations of adrenal venous sampling, including its high cost, scarce availability, technical challenges, and lack of standardized protocols, have driven efforts to develop alternative, non-invasive tools for the diagnosis of aldosterone producing adenomas. Seminal discoveries regarding the pathogenesis of aldosterone producing adenomas made over the past decade have leveraged hypotheses-driven research of steroid phenotypes characteristic of various aldosterone producing adenomas. In parallel, the expanding availability of mass spectrometry has enabled the simultaneous quantitation of many steroids in single assays from small volume biosamples. Steroid profiling has contributed to our evolving understanding about the pathophysiology of primary aldosteronism and its subtypes. Herein, we review the current state of knowledge regarding the application of multi-steroid panels in assisting with primary aldosteronism subtyping.

Indexed as

Diagnostic Techniques, EndocrineAdrenal Cortex NeoplasmsAdrenocortical AdenomaChromatography, LiquidDiagnosis, DifferentialHumansHyperaldosteronismMetabolomeMetabolomicsSteroidsTandem Mass SpectrometrySteroids

Identifiers

PMID32330948
PMCPMC7924960
OpenAlexW3019506304

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.