Evidence map›Paper›PMID 32330679›Full record

ArticleBiomedical journal2021

Typical and atypical enteropathogenic Escherichia coli in children with acute diarrhoea: Changing trend in East Delhi.

K Snehaa, Taru Singh, Sajad Ahmad Dar, Shafiul Haque, Vishnampettai G Ramachandran, Rumpa Saha, Dheeraj Shah, Shukla Das

Open access · goldAbstract read
In one paragraph

Article in Biomedical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  7. Review
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  13. Prevalence of Multidrug-Resistant DiarrheagenicAntibiotics (Basel, Switzerland) · 2022
    Review
  14. Occurrence ofFrontiers in microbiology · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Pathophysiology of EnteropathogenicNewborn (Clarksville, Md.)
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

K SnehaaDepartment of Microbiology, University College of Medical Sciences (University of Delhi), Guru Teg Bahadur Hospital, Delhi, India.
Taru SinghDepartment of Microbiology, University College of Medical Sciences (University of Delhi), Guru Teg Bahadur Hospital, Delhi, India.
Sajad Ahmad DarDepartment of Microbiology, University College of Medical Sciences (University of Delhi), Guru Teg Bahadur Hospital, Delhi, India; Research and Scientific Studies Unit, College of Nursing & Allied Health Sciences, Jazan University, Jazan, Saudi Arabia.
Shafiul HaqueResearch and Scientific Studies Unit, College of Nursing & Allied Health Sciences, Jazan University, Jazan, Saudi Arabia.
Vishnampettai G RamachandranDepartment of Microbiology, University College of Medical Sciences (University of Delhi), Guru Teg Bahadur Hospital, Delhi, India.
Rumpa SahaDepartment of Microbiology, University College of Medical Sciences (University of Delhi), Guru Teg Bahadur Hospital, Delhi, India.
Dheeraj ShahDepartment of Paediatrics, University College of Medical Sciences (University of Delhi), Guru Teg Bahadur Hospital, Delhi, India.
Shukla DasDepartment of Microbiology, University College of Medical Sciences (University of Delhi), Guru Teg Bahadur Hospital, Delhi, India. Electronic address: shukladas_123@yahoo.com.
University of Delhi · INJazan University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWorldwide around 2 million deaths occur every year due to diarrhoeal illnesses among children less than 5 years of age. Among diarrhoeagenic Escherichia coli, Enteropathogenic E. coli (EPEC) is highly prevalent in both community and hospital settings and is one of the main causes of persistent diarrhea in children in developing countries. EPEC remains underdiagnosed in India due to lack of conventional tools for identification.

methodsWe in this study investigated the prevalence and regional variation of EPEC in paediatric population suffering from diarrhoea in East Delhi, India. Two hundred stool samples were collected from children, aged between 0.5 and 5 years, with acute diarrhoea. E. coli were identified by conventional tests and PCR.

resultsWe observed 7% atypical EPEC (aEPEC) and 2.5% typical EPEC (tEPEC), with an overall 9.5% EPEC prevalence amongst total samples. E. coli phylogenetic group A was the predominant. The most common age group affected was 6-23 months with common symptoms being vomiting, watery diarrhoea and severe dehydration. High drug resistance pattern was observed in EPEC isolates.

conclusionThe study depicts a changing trend of aEPEC over tEPEC in children less than 5 years with diarrhoea, an emerging drug resistant enteropathogen and a public health concern demanding monitoring and surveillance.

Indexed as

Enteropathogenic Escherichia coliEscherichia coli InfectionsEscherichia coli ProteinsChildChild, PreschoolDiarrheaHumansIndiaInfantInfant, NewbornPhylogenyEscherichia coli ProteinsBundle forming pilus (bfp)ChildrenDiarrhoeaE. coli attaching and effacing gene (eae)Enteropathogenic Escherichia coli (EPEC)

Identifiers

PMID32330679
PMCPMC8514793
OpenAlexW3020028865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.