Evidence map›Paper›PMID 32330491›Full record

ReviewThe American journal of medicine2020

Intermittent Fasting: A Heart Healthy Dietary Pattern?

Tiffany A Dong, Pratik B Sandesara, Devinder S Dhindsa, Anurag Mehta, Laura C Arneson, Allen L Dollar, Pam R Taub, Laurence S Sperling

Abstract readReview
In one paragraph

Review in The American journal of medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
  11. Trial
  12. Trial
  13. Influence of an acute fast on ambulatory blood pressure and autonomic cardiovascular control.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Trial
  14. Trial
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tiffany A DongDepartment of Medicine; Emory Clinical Cardiovascular Research Institute.
Pratik B SandesaraEmory Clinical Cardiovascular Research Institute; Division of Cardiology, Emory University, Emory School of Medicine, Atlanta, Ga.
Devinder S DhindsaEmory Clinical Cardiovascular Research Institute; Division of Cardiology, Emory University, Emory School of Medicine, Atlanta, Ga.
Anurag MehtaEmory Clinical Cardiovascular Research Institute; Division of Cardiology, Emory University, Emory School of Medicine, Atlanta, Ga.
Laura C ArnesonDepartment of Medicine at Northwestern University Feinberg School of Medicine, Chicago, Ill.
Allen L DollarDivision of Cardiology, Emory University, Emory School of Medicine, Atlanta, Ga.
Pam R TaubDivision of Cardiovascular Medicine, UC San Diego School of Medicine, La Jolla, Calif.
Laurence S SperlingEmory Clinical Cardiovascular Research Institute; Division of Cardiology, Emory University, Emory School of Medicine, Atlanta, Ga. Electronic address: lsperli@emory.edu.

Funding

Impact of Time-Restricted Feeding (TRF) on Glucose Homeostasis and Mitochondrial Function in Patients with Metabolic SyndromeR01DK118278 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pam Rajendran Taub · 2018 to 2026
$5.3M
NIDDK NIH HHS R01 DK118278
6 · The paper itself

Abstract

Dietary patterns, such as the Dietary Approaches to Stop Hypertension (DASH) and the Mediterranean diet, have been shown to improve cardiac health. Intermittent fasting is another type of popular dietary pattern that is based on timed periods of fasting. Two different regimens are alternative day fasting and time-restricted eating. Although there are no large, randomized control trials examining the relationship between intermittent fasting and cardiovascular outcomes, current human studies that suggest this diet could reduce the risk for cardiovascular disease with improvement in weight control, hypertension, dyslipidemia, and diabetes. Intermittent fasting may exert its effects through multiple pathways, including reducing oxidative stress, optimization of circadian rhythms, and ketogenesis. This review evaluates current literature regarding the potential cardiovascular benefits of intermittent fasting and proposes directions for future research.

Indexed as

Cardiovascular DiseasesCircadian RhythmDiabetes MellitusDiet, KetogenicDyslipidemiasFastingHumansHypertensionKetone BodiesObesityOxidative StressRisk FactorsRisk Reduction BehaviorKetone BodiesAlternative day fastCircadianDiabetesDyslipidemiaHypertensionTime-restricted feeding

Identifiers

PMID32330491
PMCPMC7415631

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.