Evidence map›Paper›PMID 32330261›Full record

ArticleJournal of travel medicine2020

Zika among international travellers presenting to GeoSentinel sites, 2012-2019: implications for clinical practice.

Kristina M Angelo, Rhett J Stoney, Gaelle Brun-Cottan, Karin Leder, Martin P Grobusch, Natasha Hochberg, Susan Kuhn, Emmanuel Bottieau, Patricia Schlagenhauf, Lin Chen and 14 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of travel medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
23.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 143 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. A Review of the Recent Epidemiology of Zika Virus Infection.The American journal of tropical medicine and hygiene · 2025
    Review
  6. Article
  7. Article
  8. Monoclonal antibody applications in travel medicine.Tropical diseases, travel medicine and vaccines · 2024
    Review
  9. Human mobility and the infectious disease transmission: A systematic review.Geo-spatial information science = Diqui kongjian xinxi kexue xuebao · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. What Is the Impact of Lockdowns on Dengue?Current infectious disease reports · 2021
    Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 19 institutions in 12 countries.

Kristina M AngeloDivision of Global Migration and Quarantine, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.
Rhett J StoneyDivision of Global Migration and Quarantine, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.
Gaelle Brun-CottanDepartment of Medicine, Boston University School of Medicine, 72 E Concord St, Boston, MA 02118, USA.
Karin LederSchool of Public Health and Preventive Medicine, Victorian Infectious Disease Service, Royal Melbourne Hospital, Doherty Institute for Infection and Immunity, Monash University, 300 Grattan St, Parkville 3050, Australia.
Martin P GrobuschCenter for Tropical Medicine and Travel Medicine, Amsterdam University Medical Centers, University of Amsterdam, 1012 WX Amsterdam, The Netherlands.
Natasha HochbergDepartment of Pediatrics, Boston University School of Medicine, 72 E Concord St, Boston, MA 02118, USA.
Susan KuhnDepartment of Pediatrics, Alberta Health Services, 10101 Southport Rd SW, Calgary AB T2W 3N2, Canada.
Emmanuel BottieauDepartment of Clinical Sciences, Institute of Tropical Medicine, Kronenburgstraat 43, 2000 Antwerp, Belgium.
Patricia SchlagenhaufWHO Collaborating Centre for Travellers' Health, Epidemiology, Biostatistics, and Prevention Institute, University of Zurich, Rämistrasse 71, 8006 Zurich, Switzerland.
Lin ChenDivision of Infectious Diseases and Travel Medicine, Mount Auburn Hospital, Cambridge and Harvard Medical School, 25 Shattuck St, Boston, MA 02115, USA.
Noreen A HynesJohns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA.
Cecilia Perret PerezSchool of Medicine, Universidad Catolica de Chile, Av Libertador Bernardo O'Higgins 340, Santiago, Santiago Metropolitan, Chile.
Frank P MockenhauptCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Tropical Medicine and International Health, Augustenburger Pl. 1, 13353 Berlin, Germany.
Israel MolinaDepartment of Infectious Diseases, Vall d'Hebron University Hospital, Universitat Autónoma de Barcelona, PROSICS, Campus de la UAB, Plaça Cívica, 08193, Barcelona, Spain.
Clara Crespillo-AndújarNational Referral Unit for Tropical and Travel Medicine, Department of Internal Medicine, University Hospital La Paz-Carlos III, Paseo de la Castellana, 261, 28046 Madrid, Spain.
Denis MalvyDepartment for Infectious Diseases and Tropical Medicine, University Hospital Centre of Bordeaux, and Inserm 1219, University of Bordeaux, 146 Rue Léo Saignat, 33076 Bordeaux, France.
Eric CaumesHôpital Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.
Pierre PlourdeUniversity of Manitoba, 66 Chancellors Cir, Winnipeg MB R3T 2N2, Canada.
Marc ShawJames Cook University, 1 James Cook Dr, Douglas, Townsville 4811, Australia.
Anne E McCarthyDepartment of Medicine, Ottawa Hospital, University of Ottawa, 75 Laurier Ave E, Ottawa K1N 6N5, Canada.
Nancy Piper-JenksHRH Care, 1037 Main St, Peekskill, NY 10566, USA.
Bradley A ConnorThe New York Center for Travel and Tropical Medicine, Weill Cornell Medical College, 1300 York Ave, New York, NY 10065, USA.
Davidson H HamerDepartment of Global Health, Boston University School of Public Health, 715 Albany St, Boston, MA 02118, USA.
Annelies Wilder-SmithDepartment of Epidemiology and Global Health, University of Umea, Petrus Laestadius Väg, 901 87, Umeå, Sweden.
Boston University · USCenters for Disease Control and Prevention · USAlberta Health Services · CAAmsterdam University Medical Centers · NLCornell University · USHospital Universitario La Paz · ESHumboldt-Universität zu Berlin · DEInstituut voor Tropische Geneeskunde · BEJohns Hopkins University · USMount Auburn Hospital · USSorbonne Université · FRThe Royal Melbourne Hospital · AUUniversitat Autònoma de Barcelona · ESUniversité de Bordeaux · FRUniversity of London · GBUniversity of Manitoba · CAUniversity of Ottawa · CAUniversity of Zurich · CHWorldwise Travellers Health & Vaccination Centres · NZ

Funding

Intramural CDC HHS CC999999NCEZID CDC HHS U50 CK000189
6 · The paper itself

Abstract

introductionInternational travellers contribute to the rapid spread of Zika virus (ZIKV) and its sentinel identification globally. We describe ZIKV infections among international travellers seen at GeoSentinel sites with a focus on ZIKV acquired in the Americas and the Caribbean, describe countries of exposure and traveller characteristics, and assess ZIKV diagnostic testing by site.

methodsRecords with an international travel-related diagnosis of confirmed or probable ZIKV from January 2012 through December 2019 reported to GeoSentinel with a recorded illness onset date were included to show reported cases over time. Records from March 2016 through December 2019 with an exposure region of the Americas or the Caribbean were included in the descriptive analysis. A survey was conducted to assess the availability, accessibility and utilization of ZIKV diagnostic tests at GeoSentinel sites.

resultsGeoSentinel sites reported 525 ZIKV cases from 2012 through 2019. Between 2012 and 2014, eight cases were reported, and all were acquired in Asia or Oceania. After 2014, most cases were acquired in the Americas or the Caribbean, a large decline in ZIKV cases occurred in 2018-19.Between March 2016 and December 2019, 423 patients acquired ZIKV in the Americas or the Caribbean, peak reporting to these regions occurred in 2016 [330 cases (78%)]. The median age was 36 years (range: 3-92); 63% were female. The most frequent region of exposure was the Caribbean (60%). Thirteen travellers were pregnant during or after travel; one had a sexually acquired ZIKV infection. There was one case of fetal anomaly and two travellers with Guillain-Barré syndrome. GeoSentinel sites reported various challenges to diagnose ZIKV effectively.

conclusionZIKV should remain a consideration for travellers returning from areas with risk of ZIKV transmission. Travellers should discuss their travel plans with their healthcare providers to ensure ZIKV prevention measures are taken.

Indexed as

Travel-Related IllnessZika Virus InfectionAdultAmericasAsiaCaribbean RegionFemaleHumansMalePregnancyZika Virusdeclining epidemicGuillain-Barre syndromesentinel surveillanceSurveyZika diagnostics

Identifiers

PMID32330261
PMCPMC7604850
OpenAlexW3017512947

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.