Evidence map›Paper›PMID 32329907›Full record

ArticleAnnals of the New York Academy of Sciences2020

Cutaneous lewisite exposure causes acute lung injury.

Shajer Manzoor, Nithya Mariappan, Iram Zafar, Chih-Chang Wei, Aamir Ahmad, Ranu Surolia, Jeremy B Foote, Anupam Agarwal, Shama Ahmad, Mohammad Athar and 2 more

Open access · greenAbstract read
In one paragraph

Article in Annals of the New York Academy of Sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  5. Article
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  7. Article
  8. A Murine Model of Vesicant-Induced Acute Lung Injury.The Journal of pharmacology and experimental therapeutics · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. MicroRNA-1224-5p Aggravates Sepsis-Related Acute Lung Injury in Mice.Oxidative medicine and cellular longevity · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Shajer ManzoorDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Nithya MariappanDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Iram ZafarDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Chih-Chang WeiDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Aamir AhmadDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Ranu SuroliaDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Jeremy B FooteDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Anupam AgarwalDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Shama AhmadDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-1049-5054
Mohammad AtharDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama.
Veena B AntonyDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Aftab AhmadDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-0686-0987
University of Alabama at Birmingham · US

Funding

UAB Research Center of Excellence in ArsenicalsU54ES030246 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ATHAR, MOHAMMAD · 2018 to 2022
$19.0M
Blocking Arsenicals-induced Cutaneous InjuryU01NS095678 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ATHAR, MOHAMMAD · 2015 to 2019
$3.8M
Extracellular RNA as therapeutic target after toxic chemical inhalationU01ES025069 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AHMAD, AFTAB · 2014 to 2019
$2.5M
Hypoxic factors in pulmonary hypertensionR01HL114933 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI AHMAD, AFTAB · 2014 to 2018
$1.5M
Targeting cardiopulmonary calpains to mitigate toxicity of halogen gases.U01ES028182 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AHMAD, SHAMA, DELL'ITALIA, LOUIS J. · 2017 to 2019
$1.3M
The Kallikrein/Kinin-Mast Cell Interaction in Volume OverloadI01BX001050 · VA · BIRMINGHAM VA MEDICAL CENTER · PI WEI, CHIH-CHANG KEVIN · 2011 to 2014
–
BLRD VA I01 BX001050NHLBI NIH HHS R01 HL114933NIEHS NIH HHS U01 ES025069NIEHS NIH HHS U01 ES028182NIEHS NIH HHS U54 ES030246NINDS NIH HHS U01 NS095678
6 · The paper itself

Abstract

Lewisite is a strong vesicating and chemical warfare agent. Because of the rapid transdermal absorption, cutaneous exposure to lewisite can also elicit severe systemic injury. Lewisite (2.5, 5.0, and 7.5 mg/kg) was applied to the skin of Ptch1

Indexed as

Acute Lung InjuryArsenicalsLungNeutrophilsAnimalsBronchoalveolar LavageChemical Warfare AgentsCytokinesFemaleLeukocyte CountMaleMiceMice, HairlessNeutrophil InfiltrationPlatelet CountSkinArsenicalsChemical Warfare AgentsCytokineslewisiteacute lung injuryARDScutaneousinflammationlewisite

Identifiers

PMID32329907
PMCPMC8325512
OpenAlexW3018117392

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.