Evidence map›Paper›PMID 32329629›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2.

Guoshuai Cai, Yohan Bossé, Feifei Xiao, Farrah Kheradmand, Christopher I Amos

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 203 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
203citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

203 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Impact of Glucose, Inflammation and Phytochemicals onAntioxidants (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Long-Term Effects of COVID-19 on Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Advances in laboratory medicine · 2023
    Article

143 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Guoshuai CaiUniversity of South CarolinaColumbia, South Carolina.
Yohan BosséLaval UniversityQuebec City, Quebec, Canada.ORCID 0000-0002-3067-3711
Feifei XiaoUniversity of South CarolinaColumbia, South Carolina.
Farrah KheradmandU.S. Department of Veterans AffairsHouston, Texasand.
Christopher I AmosBaylor College of MedicineHouston, Texas.

Funding

Translating Molecular and Clinical Data to Population Lung Cancer Risk AssessmentU19CA203654 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Christopher I. Amos · 2017 to 2026
$23.7M
Pathogenesis of Polymicrobial Cerebritis-Related DementiaR01AI135803 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI CORRY, DAVID B, KHERADMAND, FARRAH · 2018 to 2022
$3.8M
Toxic Effects of Ecigs Following Transition From Conventional CigarettesR01ES029442 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI KHERADMAND, FARRAH · 2018 to 2020
$1.6M
Regulation of Innate and Adaptive Immunity in Human COPD and EmphysemaI01CX000104 · VA · MICHAEL E DEBAKEY VA MEDICAL CENTER · PI KHERADMAND, FARRAH · 2009 to 2021
–
CSRD VA I01 CX000104NCI NIH HHS U19 CA203654NIAID NIH HHS R01 AI135803NIEHS NIH HHS R01 ES029442
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiotensin-Converting Enzyme 2Asian PeopleBetacoronavirusCoronavirus InfectionsCOVID-19Databases, GeneticEx-SmokersFurinGene Expression ProfilingHumansLungNon-SmokersPandemicsPeptidyl-Dipeptidase APneumonia, ViralPulmonary Disease, Chronic ObstructiveACE2 protein, humanAngiotensin-Converting Enzyme 2FurinFURIN protein, humanPeptidyl-Dipeptidase ASerine EndopeptidasesTMPRSS2 protein, human

Identifiers

PMID32329629
PMCPMC7301735

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.