Evidence map›Paper›PMID 32329613›Full record

ArticleJournal of the American Society for Mass Spectrometry2020

Evaluation of Data Analysis Platforms and Compatibility with MALDI-TOF Imaging Mass Spectrometry Data Sets.

Gordon T Luu, Alanna R Condren, Lisa Juliane Kahl, Lars E P Dietrich, Laura M Sanchez

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gordon T LuuDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Alanna R CondrenDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Lisa Juliane KahlDepartment of Biological Sciences, Columbia University, New York, New York 10027, United States.
Lars E P DietrichDepartment of Biological Sciences, Columbia University, New York, New York 10027, United States.
Laura M SanchezDepartment of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID http://orcid.org/0000-0001-9223-7977

Funding

Research Training in Natural Product Complementary and Integrative HealthT32AT007533 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Joanna E Burdette, JIMMY ORJALA · 2013 to 2026
$4.3M
Integration of redox-balancing mechanisms in Pseudomonas aeruginosa biofilmsR01AI103369 · NIAID · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DIETRICH, LARS · 2013 to 2022
$4.1M
NCCIH NIH HHS T32 AT007533NIAID NIH HHS R01 AI103369
6 · The paper itself

Abstract

Imaging mass spectrometry (IMS) has proven to be a useful tool when investigating the spatial distributions of metabolites and proteins in a biological system. One of the biggest advantages of IMS is the ability to maintain the 3D chemical composition of a sample and analyze it in a label-free manner. However, acquiring the spatial information leads to an increase in data size. Due to the increased availability of commercial mass spectrometers capable of IMS, there has been an exciting development of different statistical tools that can help decipher the spatial relevance of an analyte in a biological sample. To address this need, software packages like SCiLS and the open source R package Cardinal have been designed to perform unbiased spectral grouping based on the similarity of spectra in an IMS data set. In this note, we evaluate SCiLS and Cardinal compatibility with MALDI-TOF IMS data sets of the Gram-negative pathogen

Indexed as

Cardinaldata analysisdata processingimaging mass spectrometryMALDI-TOFSCiLS

Identifiers

PMID32329613
PMCPMC7275808

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.