ArticleCancer medicine2020
Associations between prostate cancer-related anxiety and health-related quality of life.
Article in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effectiveness of psychological intervention for depression, anxiety, and distress in prostate cancer: a systematic review of literature.Prostate cancer and prostatic diseases · 2021Pooled it
- Cognitive-behavioral stress management program reduces postoperative psychological pressure and improves life quality in prostate cancer patients.Irish journal of medical science · 2024Trial
- Association between comorbid anxiety and depression symptomatology, quality of life, social support and use of mental health services in youth from Bogota, Buenos Aires, and Lima.Journal of affective disorders · 2026Article
- Causal Relationship Between Anxiety Disorders and Cancers: A Bidirectional Two-Sample Mendelian Randomization Study.Brain and behavior · 2025Article
- Physical activity and health-related quality of life among men with prostate cancer living in remote areas of Quebec A cross-sectional, observational study.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025Article
- Key Determinants Influencing Treatment Decision-Making for and Adherence to Active Surveillance for Prostate Cancer: A Systematic Review.Journal of personalized medicine · 2025Review
- Network Analysis of Anxiety in Prostate Cancer Patients.Psycho-oncology · 2025Article
- Health-related quality of life and fear of progression in individuals with Li-Fraumeni syndrome.Journal of genetic counseling · 2025Article
- Self-rated health and health-related quality of life among cancer patients: the serial multiple mediation of anxiety and depression.BMC psychology · 2024Article
- Prostate cancer-related anxiety among long-term survivors after radical prostatectomy: A longitudinal study.Cancer medicine · 2023Article
- Health-related quality of life with enzalutamide versus flutamide in castration-resistant prostate cancer from the AFTERCAB study.International journal of clinical oncology · 2022Article
- Prostate Cancer Eligible for Radical Prostatectomy: Self-Esteem of Patients and Forms of Coping with Stress.International journal of environmental research and public health · 2022Article
- Causes of Death after Prostate Cancer Diagnosis: A Population-Based Study.Oxidative medicine and cellular longevity · 2022Article
- Anxiety, depression and quality of life: a longitudinal study involving cancer patient-caregiver dyads.Health psychology report · 2022Article
- Efficacy of a Combined Acceptance and Commitment Intervention to Improve Psychological Flexibility and Associated Symptoms in Cancer Patients: Study Protocol for a Randomized Controlled Trial.Frontiers in psychology · 2022Article
- Racial Disparities and Mental Health Effects Within Prostate Cancer.Health psychology research · 2022Article
- Mapping the Memorial Anxiety Scale for Prostate Cancer to the SF-6D.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Associations between prostate cancer-related anxiety and health-related quality of life.Cancer medicine · 2020Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundThere are uncertainties about prostate cancer-related anxiety's (PCRA) associations with health-related quality of life (HRQOL) and major depression, and these could affect the quality of mental healthcare provided to prostate cancer patients. Addressing these uncertainties will provide more insight into PCRA and inform further research on the value of PCRA prevention. The goals of this study were to measure associations between PCRA and HRQOL at domain and subdomain levels, and to evaluate the association between PCRA and probable (ie, predicted major) depression.
methodWe analyzed secondary cross-sectional data from the North Carolina Prostate Cancer Comparative Effectiveness & Survivorship Study (NC ProCESS-a population-based cohort of prostate cancer patients enrolled shortly after diagnosis [between January 2011 and June 2013] and followed prospectively). Patient-reported measures of PCRA and HRQOL from 1,016 enrollees who participated in NC ProCESS's 1-year follow-up survey were assessed. Outcomes of interests were a) linear correlations between contemporaneous memorial anxiety scale for prostate cancer (MAX-PC) and Short Form 12 (SF-12) scores, and b) measures of association between indicators of clinically significant PCRA (ie, MAX-PC > 27) and probable depression during survey contact (ie, SF-12 mental component score ≤43).
resultsPCRA measures had notable associations with SF-12's mental health subscale (assesses low mood/nervousness [rho = -0.42]) and emotional role functioning subscale (assesses subjective productivity loss [rho = -0.46]). Additionally, the risk of probable depression was significantly higher in participants with clinically significant PCRA compared with those without it (weighed risk ratio = 5.3, 95% confidence interval 3.6-7.8; P < .001).
conclusionProstate cancer patients with clinically significant PCRA should be assessed for major depression and productivity loss.
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