Evidence map›Paper›PMID 32328990›Full record

ArticleEuropean journal of epidemiology2020

The Dementias Platform UK (DPUK) Data Portal.

Sarah Bauermeister, Christopher Orton, Simon Thompson, Roger A Barker, Joshua R Bauermeister, Yoav Ben-Shlomo, Carol Brayne, David Burn, Archie Campbell, Catherine Calvin and 56 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Observational
  2. Review
  3. Solving the 'Goldilocks problem' in dementia clinical trials with multimodal AI.The journal of prevention of Alzheimer's disease · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. We must discuss research environments.Royal Society open science · 2024
    Article
  14. Dementias Platform UK: Bringing genetics into life.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  15. Article
  16. Article
  17. Artificial intelligence for dementia prevention.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

66 authors.

Sarah BauermeisterDepartment of Psychiatry, University of Oxford, Oxford, UK.
Christopher OrtonSwansea University Medical School, Swansea University, Swansea, UK.
Simon ThompsonSwansea University Medical School, Swansea University, Swansea, UK.
Roger A BarkerCambridge University Department of Clinical Neurosciences and Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Joshua R BauermeisterDepartment of Psychiatry, University of Oxford, Oxford, UK.
Yoav Ben-ShlomoPopulation Health Sciences, University of Bristol, Bristol, UK.
Carol BrayneDepartment of Public Health, University of Cambridge, Cambridge, UK.
David BurnFaculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Archie CampbellDepartment of Medical Genetics, University of Edinburgh, Edinburgh, UK.
Catherine CalvinDepartment of Psychiatry, University of Oxford, Oxford, UK.
Siddharthan ChandranCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Nishi ChaturvediMRC Unit for Lifelong Health and Ageing, UCL, London, UK.
Geneviève ChêneBordeaux Population Health, Université Bordeaux, Bordeaux, France.
Iain P ChessellNeuroscience BioPharma R&D, AstraZeneca, Cambridge, UK.
Anne CorbettCollege of Medicine and Health, University of Exeter, Exeter, UK.
Daniel H J DavisMRC Unit for Lifelong Health and Ageing, UCL, London, UK.
Mike DenisOxford Academic Health Science Network, University of Oxford, Oxford, UK.
Carole DufouilBordeaux Population Health, Université Bordeaux, Bordeaux, France.
Paul ElliottMRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Nick FoxDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Derek HillKing's College London, London, UK.
Scott M HoferDepartment of Psychology, University of Victoria, Victoria, Canada.
Michele T HuNuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
Christoph JindraDepartment of Psychiatry, University of Oxford, Oxford, UK.
Frank KeeCentre for Public Health, Queen's University Belfast, Belfast, UK.
Chi-Hun KimDepartment of Psychiatry, University of Oxford, Oxford, UK.
Changsoo KimDepartment of Preventive Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Mika KivimakiInstitute of Epidemiology and Health, University College London, London, UK.
Ivan KoychevDepartment of Psychiatry, University of Oxford, Oxford, UK.
Rachael A LawsonTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Gerry J LindenCentre for Public Health, Queen's University Belfast, Belfast, UK.
Ronan A LyonsSwansea University Medical School, Swansea University, Swansea, UK.
Clare MackayDepartment of Psychiatry, University of Oxford, Oxford, UK.
Paul M MatthewsDivision of Brain Sciences and UK Dementia Research Institute, Imperial College London, London, UK.
Bernadette McGuinessCentre for Public Health, Queen's University Belfast, Belfast, UK.
Lefkos MiddletonMRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Catherine MoodyMedical Research Council, Swindon, UK.
Katrina MooreDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Duk L NaDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
John T O'BrienDepartment of Psychiatry, University of Cambridge, Cambridge, UK.
Sebastien OurselinSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Shantini ParanjothySchool of Medicine, Cardiff University, Cardiff, UK.
Ki-Soo ParkInstitute of Health Science, Gyeongsang National University, Jinju-si, South Korea.
David J PorteousInstitute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
Marcus RichardsMRC Unit for Lifelong Health and Ageing, UCL, London, UK.
Craig W RitchieCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Jonathan D RohrerDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Martin N RossorDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
James B RoweCambridge University Department of Clinical Neurosciences and Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Rachael ScahillDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Christian SchnierUsher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
Jonathan M SchottDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Sang W SeoDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Matthew SouthDepartment of Psychiatry, University of Oxford, Oxford, UK.
Matthew SteptoeDepartment of Behavioural Science and Health, UCL, London, UK.
Sarah J TabriziDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Andrea TalesCentre for Innovative Ageing, Swansea University, Swansea, UK.
Therese TillinUCL Institute for Cardiovascular Science, London, UK.
Nicholas J TimpsonPopulation Health Sciences, University of Bristol, Bristol, UK.
Arthur W TogaLaboratory of Neuro Imaging, USC, Los Angeles, USA.
Pieter-Jelle VisserVU University Medical Centre, Maastricht University, Maastricht, The Netherlands.
Richard Wade-MartinsDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Tim WilkinsonUsher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
Julie WilliamsInstitute of Psychological Medicine and Clinical Neurosciences, and UK Dementia Research Institute, Cardiff University, Cardiff, UK.
Andrew WongMRC Unit for Lifelong Health and Ageing, UCL, London, UK.
John E J GallacherDepartment of Psychiatry, University of Oxford, Oxford, UK. john.gallacher@psych.ox.ac.uk.ORCID http://orcid.org/0000-0002-2394-5299

Funding

Medical Research Council G0300429Medical Research Council G0600237Medical Research Council G0902227Medical Research Council MC_EX_MR/N50192X/1Medical Research Council MC_PC_15018Medical Research Council MC_PC_17112Medical Research Council MC_PC_19009Medical Research Council MC_UU_00005/12Medical Research Council MC_UU_00019/1Medical Research Council MC_UU_00019/3Medical Research Council MC_UU_12019/3Medical Research Council MR/K013041/1Medical Research Council MR/L01341X/1Medical Research Council MR/L023784/1Medical Research Council MR/L023784/2Medical Research Council MR/M009076/1Medical Research Council MR/M024962/1Medical Research Council MR/N029453/1Medical Research Council MR/P007058/1Medical Research Council MR/R023484/1Medical Research Council MR/S019669/1Parkinson's UK H-1301Parkinson's UK J-0901Wellcome Trust 107467/Z/15/ZWellcome Trust 202802/Z/16/Z
6 · The paper itself

Abstract

The Dementias Platform UK Data Portal is a data repository facilitating access to data for 3 370 929 individuals in 42 cohorts. The Data Portal is an end-to-end data management solution providing a secure, fully auditable, remote access environment for the analysis of cohort data. All projects utilising the data are by default collaborations with the cohort research teams generating the data. The Data Portal uses UK Secure eResearch Platform infrastructure to provide three core utilities: data discovery, access, and analysis. These are delivered using a 7 layered architecture comprising: data ingestion, data curation, platform interoperability, data discovery, access brokerage, data analysis and knowledge preservation. Automated, streamlined, and standardised procedures reduce the administrative burden for all stakeholders, particularly for requests involving multiple independent datasets, where a single request may be forwarded to multiple data controllers. Researchers are provided with their own secure 'lab' using VMware which is accessed using two factor authentication. Over the last 2 years, 160 project proposals involving 579 individual cohort data access requests were received. These were received from 268 applicants spanning 72 institutions (56 academic, 13 commercial, 3 government) in 16 countries with 84 requests involving multiple cohorts. Projects are varied including multi-modal, machine learning, and Mendelian randomisation analyses. Data access is usually free at point of use although a small number of cohorts require a data access fee.

Indexed as

Database Management SystemsData ManagementDementiaBiomedical ResearchCohort StudiesDatasets as TopicHumansUnited KingdomCohortsData accessData managementData platformData repositoryEpidemiology

Identifiers

PMID32328990
PMCPMC7320955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.