Evidence map›Paper›PMID 32328768›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2020

Added value of susceptibility-weighted imaging to diffusion-weighted imaging in the characterization of parotid gland tumors.

Jia-Suo Jiang, Liu-Ning Zhu, Wei Chen, Lu Chen, Guo-Yi Su, Xiao-Quan Xu, Fei-Yun Wu

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jia-Suo JiangDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Rd., Nanjing, People's Republic of China.
Liu-Ning ZhuDepartment of Stomatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
Wei ChenDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Rd., Nanjing, People's Republic of China.
Lu ChenDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Rd., Nanjing, People's Republic of China.
Guo-Yi SuDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Rd., Nanjing, People's Republic of China.
Xiao-Quan XuDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Rd., Nanjing, People's Republic of China. xiaoquanxu_1987@163.com.
Fei-Yun WuDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Rd., Nanjing, People's Republic of China. wfy_njmu@163.com.ORCID http://orcid.org/0000-0002-0343-0458
Jiangsu Province Hospital · CN

Funding

Advanced Software for MRI, PET, SPECT and CT Image AnalysisU24EB028980 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RUSINEK, HENRY · 2019 to 2021
$1.2M
Jiangsu Province's Young Medical Talents Program QNRC2016560National Natural Science Foundation of China 81771796NIBIB NIH HHS U24 EB028980
6 · The paper itself

Abstract

purposeTo assess the added value of susceptibility-weighted imaging (SWI) to diffusion-weighted imaging (DWI) in the characterization of parotid gland tumors.

methodsSeventy-eight patients with pathologically confirmed parotid gland tumors, who underwent DWI and SWI for pre-surgery evaluation, were enrolled. Apparent diffusion coefficient (ADC) and degree of intratumoral susceptibility signal intensity (ITSS) were measured and compared between benign and malignant groups, and among pleomorphic adenoma (PA), Warthin tumor (WT) and malignant tumor (MT). Independent sample t test, one-way analysis of variance and receiver operating characteristic curve analysis were used for statistical analyses.

resultsBenign parotid gland tumor showed a significantly higher mean ADC value than malignant tumors (0.836 ± 0.350 vs 0.592 ± 0.163, p = 0.001). Setting an average ADC value of 0.679 as the cut-off value, optimal differentiating performance could be obtained (AUC, 0.700; sensitivity, 62.69%; specificity, 81.82%) for differentiating malignant from benign tumors. PA showed significantly higher mean ADC and less ITSS than WT (ADC, p < 0.001; ITSS, p = 0.033) and MT (ADC, p < 0.001; ITSS, p = 0.024), while the difference between WT and MT was not significant (ADC, p = 0.826; ITSS, p = 0.539). After integration with ITSS, the diagnostic performance of ADC was improved for differentiating PA from WT (AUC 0.921 vs 0.873) and from MT (AUC 0.906 vs 0.882).

conclusionSWI could provide added information to DWI and serve as a supplementary imaging marker for the characterization of parotid gland tumors.

Indexed as

Parotid GlandParotid NeoplasmsDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingHumansRetrospective StudiesSensitivity and SpecificityApparent diffusion coefficientDifferentiating diagnosisDiffusion-weighted imagingParotid glandSusceptibility-weighted imaging

Identifiers

PMID32328768
OpenAlexW3018151807

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.