Evidence map›Paper›PMID 32328756›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2020

Visual outcome and poor prognostic factors in acute retinal necrosis syndrome.

Mora Paolo, Zola Marta, Favilla Stefania, Tagliavini Viola, Calzetti Giacomo, Carta Arturo, Gandolfi Stefano, Guex-Crosier Yan

Erratum issuedAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Treatment outcomes of PCR-positive acute retinal necrosis.Irish journal of medical science · 2024
    Review
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  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Mora PaoloOphthalmology Unit, University Hospital of Parma, Parma, Italy.
Zola MartaDepartment of Ophthalmology, Jules-Gonin Eye Hospital, University of Lausanne, Fondation Asile des Aveugles, Lausanne, Switzerland.
Favilla StefaniaIndependent Researcher, on behalf of the Ophthalmology Unit, University Hospital of Parma, Parma, Italy.
Tagliavini ViolaOphthalmology Unit, University Hospital of Parma, Parma, Italy.
Calzetti GiacomoOphthalmology Unit, University Hospital of Parma, Parma, Italy.
Carta ArturoOphthalmology Unit, University Hospital of Parma, Parma, Italy.
Gandolfi StefanoOphthalmology Unit, University Hospital of Parma, Parma, Italy.
Guex-Crosier YanDepartment of Ophthalmology, Jules-Gonin Eye Hospital, University of Lausanne, Fondation Asile des Aveugles, Lausanne, Switzerland. yan.guex@fa2.ch.
University of Parma · ITFondation Asile des Aveugles · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the impact of selected clinical parameters on the mid-/long-term visual outcome of patients with acute retinal necrosis (ARN)

designA retrospective cohort study

settingTwo University Hospitals (Parma, Italy; Lausanne, Switzerland).

participantsThirty-nine non-HIV patients (39 eyes) with ARN, as confirmed by polymerase chain reaction on intraocular samples. The following potential predictors were tested using linear regression models: age, sex, etiology, best-corrected visual acuity (BCVA) on admission, delay between ARN symptom onset and treatment initiation, and surgery (performed or not). MAIN OUTCOME: BCVA at the final follow up

resultsThirty-nine of 39 non-HIV patients (22 men and 17 women; mean age, 50 years) diagnosed with ARN were enrolled in the study. Etiologies were: varicella-zoster virus in 25 eyes (64%), herpes simplex viruses in the remaining 14 eyes. The average follow-up duration was 19 ± 13 months. All patients had undergone systemic antivirals; surgery was performed in 16 eyes. The mean delay between onset of visual symptoms and antiviral treatment initiation was 15 ± 31 days (range, 1-180 days). The mean BCVA at baseline was 0.83 ± 0.75 logMAR, while the mean final BCVA was 0.75 ± 0.81 logMAR. Both initial BCVA and treatment delay (TD) were significantly correlated with the final BCVA (p < 0.05).

conclusionsInitial BCVA and TD seem to be significant predictors of mid-/long-term visual outcome in non-HIV patients affected by ARN.

Indexed as

Visual AcuityAdolescentAdultAgedAged, 80 and overChildEye Infections, ViralFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetinaRetinal Necrosis Syndrome, AcuteRetrospective StudiesAcute retinal necrosis (ARN)PredictorsTreatmentVisual outcome

Identifiers

PMID32328756
OpenAlexW3018924027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.