ReviewFrontiers in molecular biosciences2020
Non-translational Connections of eEF1B in the Cytoplasm and Nucleus of Cancer Cells.
Review in Frontiers in molecular biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Function of eEF-1γ in the nucleus in response to insulin in hepatocellular carcinoma cells.Communications biology · 2025Article
- EEF1B2 regulates bone marrow-derived mesenchymal stem cells bone-fat balance via Wnt/β-catenin signaling.Cellular and molecular life sciences : CMLS · 2024Article
- Article
- The eEF1 family of mammalian translation elongation factors.BBA advances · 2023Article
- Quaternary organization of the human eEF1B complex reveals unique multi-GEF domain assembly.Nucleic acids research · 2022Article
- Localization and Functional Roles of Components of the Translation Apparatus in the Eukaryotic Cell Nucleus.Cells · 2021Review
- Eukaryotic Elongation Factor 3 ProtectsGenes · 2020Article
- Editorial: Multitasking Biomolecules in Human Pathologies: Known Players on Their Unexpected Journeys.Frontiers in medicine · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
The human translation machinery includes three types of supramolecular complexes involved in elongation of the polypeptide chain: the ribosome, complex of elongation factors eEF1B and multienzyme aminoacyl-tRNA synthetase complex. Of the above, eEF1B is the least investigated assembly. Recently, a number of studies provided some insights into the structure of different eEF1B subunits and changes in their expression in cancer and other diseases. There is increasing agreement that possible disease-related functions of eEF1B are not necessarily related to its role in translation. This mini-review focuses on structural and functional features of the eEF1B complex while paying special attention to possible non-canonical functions of its subunits in cancer cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.