Evidence map›Paper›PMID 32328474›Full record

ArticleFrontiers in public health2020

Half of Prescribed Antibiotics Are Not Needed: A Pharmacist-Led Antimicrobial Stewardship Intervention and Clinical Outcomes in a Referral Hospital in Ethiopia.

Gebremedhin Beedemariam Gebretekle, Damen Haile Mariam, Workeabeba Abebe Taye, Atalay Mulu Fentie, Wondwossen Amogne Degu, Tinsae Alemayehu, Temesgen Beyene, Michael Libman, Teferi Gedif Fenta, Cedric P Yansouni and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Gebremedhin Beedemariam GebretekleSchool of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia.
Damen Haile MariamSchool of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.
Workeabeba Abebe TayeSchool of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Atalay Mulu FentieSchool of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia.
Wondwossen Amogne DeguSchool of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Tinsae AlemayehuSchool of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Temesgen BeyeneSchool of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Michael LibmanJ. D. MacLean Centre for Tropical Diseases and McGill University, Montreal, QC, Canada.
Teferi Gedif FentaSchool of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia.
Cedric P YansouniJ. D. MacLean Centre for Tropical Diseases and McGill University, Montreal, QC, Canada.
Makeda SemretJ. D. MacLean Centre for Tropical Diseases and McGill University, Montreal, QC, Canada.
Addis Ababa University · ETMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intense antibiotic consumption in Low- and Middle-Income Countries (LMICs) is fueled by critical gaps in laboratory infrastructure and entrenched syndromic management of infectious syndromes. Few data inform the achievability and impact of antimicrobial stewardship interventions, particularly in Sub-Saharan Africa. Our goal was to demonstrate the feasibility of a pharmacist-led laboratory-supported intervention at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia, and report on antimicrobial use and clinical outcomes associated with the intervention.

Indexed as

Antimicrobial StewardshipPharmacistsAdultAnti-Bacterial AgentsChildEthiopiaHospital MortalityHospitalsHumansProspective StudiesReferral and ConsultationAnti-Bacterial AgentsAMRantimicrobial prescribingantimicrobial stewardshipaudit-feedbackEthiopiaLMICLRSpharmacist

Identifiers

PMID32328474
PMCPMC7160317
OpenAlexW3016084871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.