Evidence map›Paper›PMID 32328436›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

Advanced Near-Infrared Light for Monitoring and Modulating the Spatiotemporal Dynamics of Cell Functions in Living Systems.

Guangcun Chen, Yuheng Cao, Yanxing Tang, Xue Yang, Yongyang Liu, Dehua Huang, Yejun Zhang, Chunyan Li, Qiangbin Wang

Open access · goldAbstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 190 citations in OpenAlex.

  1. Review
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  12. Exosomes/MoSJournal of nanobiotechnology · 2025
    Article
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  16. Genetics-Based Targeting Strategies for Precise Neuromodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Guangcun ChenCAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-Lab CAS Center for Excellence in Brain Science Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China.
Yuheng CaoCAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-Lab CAS Center for Excellence in Brain Science Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China.
Yanxing TangCAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-Lab CAS Center for Excellence in Brain Science Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China.
Xue YangCAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-Lab CAS Center for Excellence in Brain Science Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China.
Yongyang LiuCAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-Lab CAS Center for Excellence in Brain Science Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China.
Dehua HuangCAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-Lab CAS Center for Excellence in Brain Science Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China.
Yejun ZhangCAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-Lab CAS Center for Excellence in Brain Science Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China.
Chunyan LiCAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-Lab CAS Center for Excellence in Brain Science Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China.
Qiangbin WangCAS Key Laboratory of Nano-Bio Interface Division of Nanobiomedicine and i-Lab CAS Center for Excellence in Brain Science Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China.ORCID https://orcid.org/0000-0001-6589-6328
University of Science and Technology of China · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light-based technique, including optical imaging and photoregulation, has become one of the most important tools for both fundamental research and clinical practice, such as cell signal sensing, cancer diagnosis, tissue engineering, drug delivery, visual regulation, neuromodulation, and disease treatment. In particular, low energy near-infrared (NIR, 700-1700 nm) light possesses lower phototoxicity and higher tissue penetration depth in living systems as compared with ultraviolet/visible light, making it a promising tool for in vivo applications. Currently, the NIR light-based imaging and photoregulation strategies have offered a possibility to real-time sense and/or modulate specific cellular events in deep tissues with subcellular accuracy. Herein, the recent progress with respect to NIR light for monitoring and modulating the spatiotemporal dynamics of cell functions in living systems are summarized. In particular, the applications of NIR light-based techniques in cancer theranostics, regenerative medicine, and neuroscience research are systematically introduced and discussed. In addition, the challenges and prospects for NIR light-based cell sensing and regulating techniques are comprehensively discussed.

Indexed as

cell function sensingliving systemsmolecular imagingnear‐infrared lightphotoregulationspatiotemporal dynamics

Identifiers

PMID32328436
PMCPMC7175256
OpenAlexW3006971738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.