ArticleComputational and mathematical methods in medicine2020
Division of Myocardial Enzyme Reference Intervals in Population Aged 1 to <18 Years Old Based on Fisher's Optimal Segmentation Method.
Article in Computational and mathematical methods in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 9 citations in OpenAlex.
- Reference intervals for 26 common biochemical analytes in term neonates in Jilin Province, China.BMC pediatrics · 2021Article
- Age- and Sex-Specific Pediatric Reference Intervals of Serum Electrolytes in Jilin Province of China Using the A Priori Approach.American journal of clinical pathology · 2020Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReference interval (RI) research is to make it a concise, effective, and practical diagnostic tool. This study aimed to establish sex- and age-specific RI for myocardial enzyme activity in population aged 1-<18 years old in Changchun, China.
methodsHealthy subjects (
resultsAST decreased gradually and was partitioned as 1, 2∼<10 and 10∼<18 years old. LDH presented disparate descending rate among 1∼<4, 4∼<12, and 12∼<18 years old. CK stood quite stable with the same RI in all ages. CKMB began to differ at 6 years of age sexually and then remained stable during 6∼<14 years old for male while it continued to decline in female. Cardiac development was partitioned as 1∼<6, 6∼<13, and 13∼<18 years old using multiple percentiles from massive data that reflect characteristics of totality as impact factors.
conclusionsFisher's optimal segmentation method excelled for multidimensionality, continuity, and loop calculating as dealing with RIs for myocardial enzymes activity and cardiac development process despite limitations. In future, impact of partition on the overall interval should be delved into.
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