ArticleFrontiers in human neuroscience2020
The Trace Conditional Learning of the Noxious Stimulus in UWS Patients and Its Prognostic Value in a GSR and HRV Entropy Study.
Article in Frontiers in human neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- The autonomic response following taVNS predicts changes in level of consciousness in DoC patients.Scientific reports · 2025Trial
- The Meaning of Pain in the Clinical Management of Patients With Disorders of Consciousness: Is It a Neglected Issue?European journal of pain (London, England) · 2026Review
- New insights and predictability from in vivo recordings of paroxysmal sympathetic hyperactivity in disorders of consciousness.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Detecting Pain Correlates With Recovery in Acute Brain Injury Patients With Disorders of Consciousness.Critical care explorations · 2025Observational
- Autonomic heart rate variability trends predict outcome in disorders of consciousness.Scientific reports · 2025Article
- Central autonomic network and early prognosis in patients with disorders of consciousness.Scientific reports · 2024Article
- Pain anticipation is a new behavioural sign of minimally conscious state.Brain communications · 2024Article
- I Feel! Therefore, I Am from Pain to Consciousness in DOC Patients.International journal of molecular sciences · 2023Review
- Heart Rate Complexity and Autonomic Modulation Are Associated with Psychological Response Inhibition in Healthy Subjects.Entropy (Basel, Switzerland) · 2023Article
- Assessment and management of pain/nociception in patients with disorders of consciousness or locked-in syndrome: A narrative review.Frontiers in systems neuroscience · 2023Review
- The Timecourse of Electrophysiological Brain-Heart Interaction in DoC Patients.Brain sciences · 2021Article
- Addressing Pain for a Proper Rehabilitation Process in Patients With Severe Disorders of Consciousness.Frontiers in pharmacology · 2021Review
- Nociceptive Response Is a Possible Marker of Evolution in the Level of Consciousness in Unresponsive Wakefulness Syndrome Patients.Frontiers in neuroscience · 2021Article
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7 authors.
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Abstract
The assessment of the consciousness level of Unresponsive Wakefulness Syndrome (UWS) patients often depends on a subjective interpretation of the observed spontaneous and volitional behavior. To date, the misdiagnosis level is around 30%. The aim of this study was to observe the behavior of UWS patients, during the administration of noxious stimulation by a Trace Conditioning protocol, assessed by the Galvanic Skin Response (GSR) and Heart Rate Variability (HRV) entropy. We recruited 13 Healthy Control (HC) and 30 UWS patients at 31 ± 9 days from the acute event evaluated by Coma Recovery Scale-Revised (CRS-R) and Nociception Coma Scale (NCS). Two different stimuli [musical stimulus (MUS) and nociceptive stimulus (NOC)], preceded, respectively by two different tones, were administered following the sequences (A) MUS1 - NOC1 - MUS2 - MUS3 - NOC2 - MUS4 - NOC3 - NOC
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