ArticleScientific reports2020
Potential Pathogenic Bacteria in Seminal Microbiota of Patients with Different Types of Dysspermatism.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05628987 (The Association of Gut Microbiota and Spermatogenic Dysfunction), which is not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Association of Gut Microbiota and Spermatogenic Dysfunction
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Is Lactobacillus spp. beneficial in human semen? Systematic review.JBRA assisted reproduction · 2025Pooled it
- Probiotics supplementation in the treatment of male infertility: A Systematic Review.JBRA assisted reproduction · 2024Pooled it
- Maternal and infant gut microbiome.iMeta · 2026Review
- Unfolding the Semen Microbiota: Implications for Male Infertility.Biomedicines · 2026Review
- Interplay of Microbiome, Oxidative Stress and Inflammation in Health and Disease.Antioxidants (Basel, Switzerland) · 2026Review
- The overlooked role of the seminovaginal microbiota in infertility: a narrative mini review.Frontiers in medicine · 2026Review
- Integrated profiling of semen microbiota and metabolome reveals dysregulation in primary idiopathic male infertility.Journal of translational medicine · 2025Article
- Beyond Genes: Mechanistic and Epidemiological Insights into Paternal Environmental Influence on Offspring Health.Current environmental health reports · 2025Review
- Article
- Lifestyle and Environmental Factors Affecting Male Fertility, Individual Predisposition, Prevention, and Intervention.International journal of molecular sciences · 2025Review
- Semen Microbiome, Male Infertility, and Reproductive Health.International journal of molecular sciences · 2025Review
- Characterizing the seminal microbiota in mature rams managed on divergent planes of nutrition, and their male offspring.Journal of animal science · 2025Article
- State-of-the-art approaches in the investigation of human seminal bacteriome using metagenomic methods.Frontiers in reproductive health · 2025Review
- DEFB119 stratifies dysbiosis with distorted networks in the seminal microbiome associated with male infertility.PNAS nexus · 2024Article
- Contribution of the seminal microbiome to paternal programming.Biology of reproduction · 2024Review
- Article
- Unraveling the Intricacies of the Seminal Microbiome and Its Impact on Human Fertility.Biology · 2024Review
- Characteristics of gut microbiota in patients with asthenozoospermia: a Chinese pilot study.BMC microbiology · 2024Article
- Effect of environmental factors on seminal microbiome and impact on sperm quality.Frontiers in endocrinology · 2024Review
- Next-Generation Sequencing to Elucidate the Semen Microbiome in Male Reproductive Disorders.Medicina (Kaunas, Lithuania) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human microbiota play an important role in the health of their human hosts. Recent studies have demonstrated that microbiota exist in seminal plasma. The current study aims to elucidate whether seminal microbiota exist in patients with different types of dysspermatism and whether bacterial biomarkers can be identified for them. A total of 159 study participants were recruited, including 22 patients with oligoasthenospermia, 58 patients with asthenospermia, 8 patients with azoospermia, 13 patients with oligospermia, and 58 matched healthy controls. Seminal microbiota composition was analyzed using 16S rRNA gene-based sequencing. The results showed that the composition of seminal microbiota of patients with dysspermatism differed from those of healthy controls. Comparison of the microbiota composition in semen samples from patients with different types of dysspermatism showed that microbiota in patients with asthenospermia and oligoasthenospermia were distinct from healthy controls in beta diversity (P < 0.05). Characteristic biomarkers, including Ureaplasma, Bacteroides, Anaerococcus, Finegoldia, Lactobacillus and Acinetobacter lwoffii, were identified based on LEfSe analysis. Inferred functional analysis based on seminal microbiome data further indicated the presence of potential pathogenic biomarkers in patients with asthenospermia and oligoasthenospermia. These results provided profiles of seminal microbiota exhibited in different types of dysspermatism, thus providing new insights into their pathogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.