ArticleNature communications2020
Photoinduced site-selective alkenylation of alkanes and aldehydes with aryl alkenes.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 182 citations in OpenAlex.
- Mechanistic Insights into Light-Driven Acceptorless Dehydrogenation Reactions.Chemical reviews · 2026Review
- Chromones as Photocatalyzed HAT Reagent and Michael Acceptor for Direct C-H Alkylation of 2-Substituted 4-Chromanones.Research (Washington, D.C.) · 2026Article
- Biomimetic Dehydrogenative Intermolecular Formal Allylic Amidation of Branched α-Olefins.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Bifunctional iron-catalyzed alkyne Z-selective hydroalkylation and tandem Z-E inversion via radical molding and flipping.Nature communications · 2024Article
- Direct ketone synthesis from primary alcohols and alkenes enabled by a dual photo/cobalt catalysis.Nature communications · 2024Article
- Synergistic Merger of Ketone, Halogen Atom Transfer (XAT), and Nickel-Mediated C(spACS organic & inorganic Au · 2024Article
- Nickel-catalysed enantioselective alkene dicarbofunctionalization enabled by photochemical aliphatic C-H bond activation.Nature catalysis · 2024Article
- Development and application of decatungstate catalyzed C-HChemical science · 2023Review
- Acceptorless cross-dehydrogenative coupling for C(spCommunications chemistry · 2023Article
- C-C bond formationChemical communications (Cambridge, England) · 2023Review
- Resurgence and advancement of photochemical hydrogen atom transfer processes in selective alkane functionalizations.Chemical science · 2023Review
- Asymmetric imino-acylation of alkenes enabled by HAT-photo/nickel cocatalysis.Chemical science · 2023Article
- Energy- and atom-efficient chemical synthesis with endergonic photocatalysis.Nature reviews. Chemistry · 2022Review
- Direct C-H Allylation of Unactivated Alkanes by Cooperative W/Cu Photocatalysis.Organic letters · 2022Article
- The Merger of Benzophenone HAT Photocatalysis and Silyl Radical-Induced XAT Enables Both Nickel-Catalyzed Cross-Electrophile Coupling and 1,2-Dicarbofunctionalization of Olefins.ACS catalysis · 2022Article
- Synthesis of New Morphinan Opioids by TBADT-Catalyzed Photochemical Functionalization at the Carbon Skeleton.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Photomediated reductive coupling of nitroarenes with aldehydes for amide synthesis.Chemical science · 2022Article
- [3+2] Cycloaddition of alkyl aldehydes and alkynes enabled by photoinduced hydrogen atom transfer.Nature communications · 2022Article
- Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfides.Nature communications · 2022Article
- Modular allylation of C(spChemical science · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dehydrogenative alkenylation of C-H bonds with alkenes represents an atom- and step-economical approach for olefin synthesis and molecular editing. Site-selective alkenylation of alkanes and aldehydes with the C-H substrate as the limiting reagent holds significant synthetic value. We herein report a photocatalytic method for the direct alkenylation of alkanes and aldehydes with aryl alkenes in the absence of any external oxidant. A diverse range of commodity feedstocks and pharmaceutical compounds are smoothly alkenylated in useful yields with the C-H partner as the limiting reagent. The late-stage alkenylation of complex molecules occurs with high levels of site selectivity for sterically accessible and electron-rich C-H bonds. This strategy relies on the synergistic combination of direct hydrogen atom transfer photocatalysis with cobaloxime-mediated hydrogen-evolution cross-coupling, which promises to inspire additional perspectives for selective C-H functionalizations in a green manner.
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