Evidence map›Paper›PMID 32327255›Full record

Trial reportOphthalmology2020

Visual Field Outcomes in the Tube Versus Trabeculectomy Study.

Swarup S Swaminathan, Alessandro A Jammal, Helen L Kornmann, Philip P Chen, William J Feuer, Felipe A Medeiros, Steven J Gedde, Tube Versus Trabeculectomy Study Group

Open access · greenAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Swarup S SwaminathanBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
Alessandro A JammalDuke Eye Center, Duke University, Durham, North Carolina.
Helen L KornmannGlaucoma Associates of Texas, Dallas, Texas.
Philip P ChenDepartment of Ophthalmology, University of Washington, Seattle, Washington.
William J FeuerBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
Felipe A MedeirosDuke Eye Center, Duke University, Durham, North Carolina.
Steven J GeddeBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida. Electronic address: sgedde@med.miami.edu.
Tube Versus Trabeculectomy Study Group
University of Miami · USDuke University · USGlaucoma Associates of Texas · USUniversity of Washington · US

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Dmitry V Ivanov · 2004 to 2026
$12.2M
NEI NIH HHS P30 EY014801
6 · The paper itself

Abstract

purposeTo describe visual field (VF) outcomes in the Tube Versus Trabeculectomy (TVT) Study.

designCohort analysis of patients in a multicenter randomized clinical trial.

participantsA total of 122 eyes of 122 patients, with 61 eyes in both the tube shunt and trabeculectomy groups.

methodsThe TVT Study is a multicenter randomized clinical trial comparing the safety and efficacy of tube shunt surgery (350-mm

main outcome measureRate of MD change during follow-up period.

resultsA total of 436 reliable VFs were analyzed, with an average of 3.6 VFs per eye. Baseline MD was -13.07 ± 8.4 decibels (dB) in the tube shunt group and -13.18 ± 8.2 dB in the trabeculectomy group (P = 0.99). The rate of change in MD was -0.60 dB/year in the tube group and -0.38 dB/year in the trabeculectomy group (P = 0.34). The 95% confidence intervals for the rates of MD change were -0.77 to -0.44 dB/year in the tube group and -0.56 to -0.20 dB/year in the trabeculectomy group. No significant difference in MD slope was seen when patients were categorized by percentage of visits with intraocular pressure (IOP) <18 mmHg or by average IOP. Univariable and multivariable risk factor analyses identified history of diabetes, elevated IOP, and worse MD as baseline factors associated with more rapid VF loss.

conclusionsSlow rates of VF loss were observed after randomized surgical treatment in the TVT Study, but no significant difference in the rate of VF loss was seen after tube shunt implantation and trabeculectomy with MMC. Patients with diabetes, higher IOP, and more severe VF loss at baseline were at higher risk for VF progression.

Indexed as

Glaucoma Drainage ImplantsTrabeculectomyAgedAged, 80 and overFemaleGlaucomaHumansIntraocular PressureMaleMiddle AgedTonometry, OcularTreatment OutcomeVision DisordersVisual AcuityVisual FieldsVisual Field Tests

Identifiers

PMID32327255
PMCPMC9289722
OpenAlexW3009745953

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.