Evidence map›Paper›PMID 32326937›Full record

ArticleBMC public health2019

The cost of influenza-associated hospitalizations and outpatient visits in Kenya.

Gideon O Emukule, Linus K Ndegwa, Michael L Washington, John W Paget, Jazmin Duque, Sandra S Chaves, Nancy A Otieno, Kabura Wamburu, Irene W Ndigirigi, Philip M Muthoka and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Gideon O EmukuleCenters for Disease Control and Prevention - Kenya Country Office, KEMRI Headquarters, Mbagathi Rd, Off Mbagathi Way, Village Market, P. O Box 606, Nairobi, 00621, Kenya. uyr9@cdc.gov.
Linus K NdegwaCenters for Disease Control and Prevention - Kenya Country Office, KEMRI Headquarters, Mbagathi Rd, Off Mbagathi Way, Village Market, P. O Box 606, Nairobi, 00621, Kenya.
Michael L WashingtonNational Center for Emerging and Zoonotic Diseases, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
John W PagetNetherlands Institute for Health Services research (NIVEL), Utrecht, The Netherlands.
Jazmin DuqueInfluenza Division, National Center for Immunization and Respiratory Diseases, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Sandra S ChavesCenters for Disease Control and Prevention - Kenya Country Office, KEMRI Headquarters, Mbagathi Rd, Off Mbagathi Way, Village Market, P. O Box 606, Nairobi, 00621, Kenya.
Nancy A OtienoKenya Medical Research Institute, Kisumu, Nairobi, Kenya.
Kabura WamburuKenya Medical Research Institute, Kisumu, Nairobi, Kenya.
Irene W NdigirigiMinistry of Health, Government of Kenya, Nyeri, Nairobi, Kenya.
Philip M MuthokaMinistry of Health, Government of Kenya, Nyeri, Nairobi, Kenya.
Koos van der VeldenRadboud University Medical Center, Department of Primary and Community care, Nijmegen, The Netherlands.
Joshua A MottCenters for Disease Control and Prevention - Kenya Country Office, KEMRI Headquarters, Mbagathi Rd, Off Mbagathi Way, Village Market, P. O Box 606, Nairobi, 00621, Kenya.
Centers for Disease Control and Prevention · KEKenya Medical Research Institute · KECenters for Disease Control and Prevention · USKenya School of Government · KEMinistry of Health · KENational Center for Emerging and Zoonotic Infectious Diseases · USNational Center for Immunization and Respiratory Diseases · USNetherlands Institute for Health Services Research · NLRadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe estimated the cost-per-episode and the annual economic burden associated with influenza in Kenya.

methodsFrom July 2013-August 2014, we recruited patients with severe acute respiratory illness (SARI) or influenza-like illness (ILI) associated with laboratory-confirmed influenza from 5 health facilities. A structured questionnaire was used to collect direct costs (medications, laboratory investigations, hospital bed fees, hospital management costs, transportation) and indirect costs (productivity losses) associated with an episode of influenza. We used published incidence of laboratory-confirmed influenza associated with SARI and ILI, and the national population census data from 2014, to estimate the annual national number of influenza-associated hospitalizations and outpatient visits and calculated the annual economic burden by multiplying cases by the mean cost.

resultsWe enrolled 275 patients (105 inpatients and 170 outpatients). The mean cost-per-episode of influenza was US$117.86 (standard deviation [SD], 88.04) among inpatients; US$114.25 (SD, 90.03) for children < 5 years, and US$137.45 (SD, 76.24) for persons aged ≥5 years. Among outpatients, the mean cost-per-episode of influenza was US$19.82 (SD, 27.29); US$21.49 (SD, 31.42) for children < 5 years, and US$16.79 (SD, 17.30) for persons aged ≥5 years. National annual influenza-associated cost estimates ranged from US$2.96-5.37 million for inpatients and US$5.96-26.35 million for outpatients.

conclusionsOur findings highlight influenza as causing substantial economic burden in Kenya. Further studies may be warranted to assess the potential benefit of targeted influenza vaccination strategies.

Indexed as

Cost of IllnessAdolescentAdultAmbulatory CareCensusesChildChild, PreschoolCosts and Cost AnalysisFemaleHealth FacilitiesHospitalizationHumansIncidenceInfantInfluenza, HumanKenyaCostCost-per-episodeEconomic burdenHospitalizationInfluenzaKenyaOutpatient

Identifiers

PMID32326937
PMCPMC6696702
OpenAlexW2944810095

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.