ArticleBMC cardiovascular disorders2020
Early detection of left atrial and bi-ventricular myocardial strain abnormalities by MRI feature tracking in normotensive or hypertensive T2DM patients with preserved LV function.
Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 30 citations in OpenAlex.
- Cardiac MRI in diabetic cardiomyopathy: translating imaging biomarkers into clinical practice.Cardiovascular diabetology · 2025Review
- CMR-based left atrial strain for predicting left ventricular diastolic dysfunction in asymptomatic hypertensive patients.Quantitative imaging in medicine and surgery · 2025Article
- Cardiac structure and function across the continuum of glucose metabolism.Physiological reports · 2025Article
- Impaired hemodynamic forces assessed by routine CMR and its determinants in different duration T2DM patients with normal LV function and myocardial strain.Frontiers in cardiovascular medicine · 2025Article
- The right ventricular dysfunction and ventricular interdependence in patients with T2DM and aortic regurgitation: an assessment using CMR feature tracking.Cardiovascular diabetology · 2024Article
- Review
- Progress in Cardiac Magnetic Resonance Feature Tracking for Evaluating Myocardial Strain in Type-2 Diabetes Mellitus.Current diabetes reviews · 2024Review
- Significant dependency of left atrial strain on left ventricular longitudinal motion.Journal of echocardiography · 2023Article
- Feature tracking cardiac magnetic resonance imaging to assess cardiac manifestations of systemic diseases.Heart failure reviews · 2023Review
- The right ventricular dysfunction and ventricular interdependence in patients with DM: assessment using cardiac MR feature tracking.Cardiovascular diabetology · 2023Article
- Assessment of left ventricular function in patients with type 2 diabetes mellitus by non-invasive myocardial work.Frontiers in endocrinology · 2023Article
- Impact of T2DM on right ventricular systolic dysfunction and interventricular interactions in patients with essential hypertension: evaluation using CMR tissue tracking.Cardiovascular diabetology · 2022Article
- Right Ventricle in Arterial Hypertension: Did We Forget Something?Journal of clinical medicine · 2022Review
- Evaluation of left ventricular systolic and diastolic function in subjects with prediabetes and diabetes using cardiovascular magnetic resonance-feature tracking.Acta diabetologica · 2022Article
- The evaluation of right ventricular function in patients with diabetes mellitus and significant stenosis at the proximal portion of the right coronary artery.Journal of ultrasound · 2022Article
- Assessment of right ventricular function using cardiovascular magnetic resonance in patients with type 2 diabetes mellitus.Quantitative imaging in medicine and surgery · 2022Article
- Diabetic cardiomyopathy: Clinical phenotype and practice.Frontiers in endocrinology · 2022Review
- Quantification of Myocardial Deformation Applying CMR-Feature-Tracking-All About the Left Ventricle?Current heart failure reports · 2021Review
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPrevious studies have found that impaired global myocardial systolic strain is associated with cardiovascular events in T2DM patients. However, the effect of hypertension (HT) on left atrial (LA), right ventricular (RV) and left ventricular (LV) myocardial deformation in hypertensive T2DM patients has not been fully studied by cardiac magnetic resonance feature tracking (CMR-FT). Our aim was to assess LA, RV and LV strain in T2DM patients with T2DM-HT and without hypertension using CMR-FT and to determine the underlying relationships with clinical parameters.
methodsA total of 27 T2DM patients, 23 T2DM-HT patients and 31 controls were studied. LA, LV and RV strain was evaluated using CMR-FT. The clinical and biochemical parameters of the patients were collected.
resultsThe T2DM patients had reduced LA global circumferential strain (LAGCS), radial strain (LAGRS), longitudinal strain (LAGLS) and right ventricular longitudinal strain (RVGLS) compared with the controls (LAGCS: 27.2 ± 2.1% vs 33.5 ± 2.4%; LAGRS: - 28.6 ± 1.1% vs - 31.9 ± 1.3%; LAGLS: 24.3 ± 1.3% vs 31.4 ± 1.5; RVGLS: - 21.4 ± 1.2% vs - 26.3 ± 1.1%, p < 0.05 for all). The T2DM-HT patients had greater LAGCS, LAGRS and LAGLS than the T2DM patients (LAGCS: 40.4 ± 3.8% vs 27.2 ± 2.1%; LAGRS: - 36.8 ± 2.0% vs - 28.6 ± 1.1%; LAGLS: 32.3 ± 2.4% vs 24.3 ± 1.3%, p < 0.05 for all). In the diabetic patients, LAGCS was associated with microalbuminuria levels (standardized ß = - 0.289, p = 0.021), and LAGCS, LAGRS and LAGLS were correlated with diuretic treatment (standardized ß =0.440, - 0.442, and 0.643, p < 0.05 for all).
conclusionsCMR-FT may be considered a promising tool for the early detection of abnormal LA and RV myocardial strain. LA and RV strain values are impaired in T2DM patients. The amelioration of LA strain might be associated with hypertensive compensation or antihypertensive treatment, which requires to be confirmed in larger trials.
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