Evidence map›Paper›PMID 32326876›Full record

ArticleUnited European gastroenterology journal2020

Surgery for Crohn's disease during pregnancy: A nationwide survey.

Adeline Germain, Thomas Chateau, Laura Beyer-Berjot, Philippe Zerbib, Zaher Lakkis, Aurélien Amiot, Anthony Buisson, David Laharie, Jérémie H Lefèvre, Stéphane Nancey and 4 more

Abstract readMulticenter Study
In one paragraph

Article in United European gastroenterology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Review
  6. Surgery for Crohn's disease during pregnancy: a difficult decision.United European gastroenterology journal · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Adeline GermainDepartment of Digestive Surgery, University Hospital of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Thomas ChateauDepartment of Hepato-Gastroenterology, University Hospital of Grenoble, University of Grenoble Alpes, France.
Laura Beyer-Berjot
Philippe ZerbibDepartment of Digestive Surgery and Transplantation, Huriez Hospital, Université Lille Nord de France, France.
Zaher LakkisDepartment of Digestive Surgery, Besançon University Hospital, France.ORCID 0000-0002-2608-5896
Aurélien AmiotDepartment of Gastroenterology, Henri Mondor Hospital, Creteil University, France.
Anthony BuissonDepartment of Gastroenterology, Estaing Hospital, Clermont-Ferrand University, France.
David LaharieDepartment of Gastroenterology, Haut-Leveque Hospital, Bordeaux University, Pessac, France.
Jérémie H LefèvreDepartment of Digestive Surgery, AP-HP, Hôpital Saint Antoine, Paris, France.ORCID 0000-0001-7601-7464
Stéphane NanceyDepartment of Gastroenterology, Lyon-Sud Hospital, Lyon University, France.
Carmen StefanescuDepartment of Gastroenterology, Beaujon Hospital, Paris Diderot University, Clichy, France.
Laurent BreslerDepartment of Digestive Surgery, University Hospital of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Laurent Peyrin-BirouletDepartment of Hepato-Gastroenterology and Inserm NGERE, University Hospital of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
GETAID Chirurgie

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsCrohn's disease (CD) frequently affects young women and may require surgery during pregnancy. Data regarding operation for CD in expectant mothers are scare. MATERIALS AND

methodsThis was a retrospective nationwide survey from the GETAID Chirurgie. Any woman with CD undergoing surgery during pregnancy was eligible.

resultsA total of 15 cases were collected between 1992 and 2015. Most operations were performed due to penetrating or stricturing complications. Mean gestational age at delivery was 34 weeks, with a mean birth weight of 2507 g. Maternal post-operative complications occurred in two-thirds of cases. Maternal mortality rate was 6.7% and neonatal mortality rate 9.1%.

conclusionsThis is the largest case series of surgery for CD during pregnancy. This operation may have significant morbidity and mortality for mother, fetus, and newborn. Indication needs to be tailored to maternal status, disease severity, and gestational age. Surgery should be managed by experienced gynecologists, physicians, and surgeons. Active CD may be associated with a greater risk to the fetus than the surgical procedure itself.

Indexed as

Pregnancy OutcomeAdultBirth WeightClinical Decision-MakingColonoscopyCrohn DiseaseFemaleFranceGestational AgeHumansInfant, NewbornMaternal MortalityPerinatal MortalityPostoperative ComplicationsPregnancyPregnancy ComplicationsCrohn’s diseasepregnancysurgery

Identifiers

PMID32326876
PMCPMC7437090

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.