Evidence map›Paper›PMID 32326730›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Assessing the Accuracy of a Deep Learning Method to Risk Stratify Indeterminate Pulmonary Nodules.

Pierre P Massion, Sanja Antic, Sarim Ather, Carlos Arteta, Jan Brabec, Heidi Chen, Jerome Declerck, David Dufek, William Hickes, Timor Kadir and 10 more

Registry-linked trialAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05968898 (Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Cancer Risk Stratification of Pulmonary Nodules), which is not on this map. Cited by 107 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05968898 narecruitingnot on this mapstarted 2024, after this paper: background citation

Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Cancer Risk Stratification of Pulmonary Nodules

TypeinterventionalSponsorAbramson Cancer Center at Penn MedicineRan2024 to 2030Enrolled300ConditionsLung Cancer, Pulmonary Nodule, SolitaryArmsOptellum Virtual Nodule Clinic
3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Risk prediction for lung cancer screening: a systematic review and meta-regression.European respiratory review : an official journal of the European Respiratory Society · 2026
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Pierre P MassionCancer Early Detection and Prevention Initiative, Vanderbilt Ingram Cancer Center, Division of Allergy, Pulmonary and Critical Care Medicine.ORCID 0000-0003-0647-0559
Sanja AnticCancer Early Detection and Prevention Initiative, Vanderbilt Ingram Cancer Center, Division of Allergy, Pulmonary and Critical Care Medicine.
Sarim AtherOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Carlos ArtetaOptellum Ltd., Oxford, United Kingdom.
Jan BrabecFaculty of Medicine, Masaryk University, Brno, Czech Republic.
Heidi ChenDepartment of Biostatistics, and.
Jerome DeclerckOptellum Ltd., Oxford, United Kingdom.
David DufekFaculty of Medicine, Masaryk University, Brno, Czech Republic.
William HickesOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Timor KadirOptellum Ltd., Oxford, United Kingdom.
Jonas KunstFaculty of Medicine, Masaryk University, Brno, Czech Republic.
Bennett A LandmanDepartment of Electrical Engineering, Vanderbilt University, Nashville, Tennessee; and.
Reginald F MundenDepartment of Radiology, Wake Forest Baptist Health, Winston Salem, North Carolina.
Petr NovotnyOptellum Ltd., Oxford, United Kingdom.
Heiko PeschlOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Lyndsey C PickupOptellum Ltd., Oxford, United Kingdom.
Catarina SantosOptellum Ltd., Oxford, United Kingdom.
Gary T SmithDepartment of Radiology, Vanderbilt University School of Medicine, Nashville, Tennessee.
Ambika TalwarOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Fergus GleesonOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

Funding

Validation of Biomarkers of Risk for the Early Detection of Lung CancerU01CA152662 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DEPPEN, STEPHEN, GROGAN, ERIC L · 2010 to 2025
$12.8M
Non-invasive evaluation of indeterminate pulmonary nodulesU01CA186145 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MASSION, PIERRE P. · 2015 to 2019
$2.0M
NCI NIH HHS U01 CA152662NCI NIH HHS U01 CA186145
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Deep LearningAlgorithmsHumansLung NeoplasmsMultiple Pulmonary NodulesNeural Networks, ComputerRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedUnited Statescomputer-aided image analysisearly detectionlung cancerneural networksrisk stratification

Identifiers

PMID32326730
PMCPMC7365375

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.