Evidence map›Paper›PMID 32326615›Full record

ArticleInternational journal of molecular sciences2020

Knockout of

Natalia Malek, Ewa Mrówczyńska, Aleksandra Michrowska, Ewa Mazurkiewicz, Iuliia Pavlyk, Antonina Joanna Mazur

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  7. Screening the receptors forFrontiers in cellular and infection microbiology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. The Cytoplasmic Actins in the Regulation of Endothelial Cell Function.International journal of molecular sciences · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Natalia MalekDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland.
Ewa MrówczyńskaDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland.ORCID 0000-0002-1204-6108
Aleksandra MichrowskaDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland.
Ewa MazurkiewiczDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland.ORCID 0000-0002-5418-5712
Iuliia PavlykDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland.
Antonina Joanna MazurDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland.
University of Wrocław · PL

Funding

National Science Center, Poland 2015/17/B/NZ3/03604
6 · The paper itself

Abstract

Non-muscle actins have been studied for many decades; however, the reason for the existence of both isoforms is still unclear. Here we show, for the first time, a successful inactivation of the

Indexed as

CRISPR-Cas SystemsActinsCell Line, TumorCell MovementFocal AdhesionsGene EditingGene Knockout TechniquesHumansLysophospholipidsMelanomaNeoplasm InvasivenessProtein IsoformsSignal TransductionStress FibersTetradecanoylphorbol AcetateACTG1 protein, humanActinslysophosphatidic acidLysophospholipidsphorbolol myristate acetateProtein IsoformsTetradecanoylphorbol Acetateactin isoformsadhesionbeta actinCRISPR/Cas9(D10A) techniquefocal adhesiongamma actinLPAmelanomamigrationPMA

Identifiers

PMID32326615
PMCPMC7216121
OpenAlexW3016336653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.