Evidence map›Paper›PMID 32326611›Full record

ArticleInternational journal of molecular sciences2020

Hedgehog Inhibitors Suppress Osteoclastogenesis in In Vitro Cultures, and Deletion of

Yukihiro Kohara, Ryuma Haraguchi, Riko Kitazawa, Yuuki Imai, Sohei Kitazawa

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Exploring the Mechanism ofBioMed research international · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Toxins · 2021
    Article
  9. Recent Advances in Osteoclast Biological Behavior.Frontiers in cell and developmental biology · 2021
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yukihiro KoharaDepartment of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan.
Ryuma HaraguchiDepartment of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan.ORCID 0000-0003-0267-5338
Riko KitazawaDepartment of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan.
Yuuki ImaiDivision of Integrative Pathophysiology, Proteo-Science Center, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan.ORCID 0000-0002-6119-0034
Sohei KitazawaDepartment of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan.
Ehime University · JPEhime University Hospital · JP

Funding

Japan Society for the Promotion of Science JP17K18438Japan Society for the Promotion of Science JP18K06832Japan Society for the Promotion of Science JP19K18514JSBMR Rising Star Grant for fiscal year 2018 Not applicable (to R.H.)
6 · The paper itself

Abstract

The functional role of the Hedgehog (Hh)-signaling pathway has been widely investigated in bone physiology/development. Previous studies have, however, focused primarily on

Indexed as

AgingAnimalsCells, CulturedCell SurvivalGene Expression Regulation, DevelopmentalHedgehog ProteinsMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutOsteoclastsOsteogenesisOsteoporosisPyridinesPyrimidinescyclopamineGANT58GANT 61Gli1 protein, mouseGli2 protein, mouseHedgehog ProteinsPyridinesPyrimidinesReceptor, Macrophage Colony-Stimulating FactorSmoothened ReceptorSmo protein, mouseThiophenesVeratrum AlkaloidsZinc Finger Protein GLI1Zinc Finger Protein Gli2cyclopamineGANT-58GANT-61GLI1GLI2Hedgehog signalingosteoclastsSmoothened

Identifiers

PMID32326611
PMCPMC7216259
OpenAlexW3016393208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.