Evidence map›Paper›PMID 32326448›Full record

ArticlePolymers2020

Hybrid Vesicle Stability under Sterilisation and Preservation Processes Used in the Manufacture of Medicinal Formulations.

Rashmi Seneviratne, Lars J C Jeuken, Michael Rappolt, Paul A Beales

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rashmi SeneviratneSchool of Chemistry, Astbury Centre for Structural Molecular Biology and Bragg Centre for Materials Research, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0001-5634-0061
Lars J C JeukenSchool of Biomedical Sciences, Astbury Centre for Structural Molecular Biology and Bragg Centre for Materials Research, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0001-7810-3964
Michael RappoltSchool of Food Science and Nutrition and Bragg Centre for Materials Research, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0001-9942-3035
Paul A BealesSchool of Chemistry, Astbury Centre for Structural Molecular Biology and Bragg Centre for Materials Research, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0001-9076-9793
University of Leeds · GB

Funding

Engineering and Physical Sciences Research Council EP/L015536/1
6 · The paper itself

Abstract

Sterilisation and preservation of vesicle formulations are important considerations for their viable manufacture for industry applications, particular those intended for medicinal use. Here, we undertake an initial investigation of the stability of hybrid lipid-block copolymer vesicles to common sterilisation and preservation processes, with particular interest in how the block copolymer component might tune vesicle stability. We investigate two sizes of polybutadiene-

Indexed as

encapsulation stabilityfiltrationfreeze-thawliposomesmembrane mechanicspolymersomes

Identifiers

PMID32326448
PMCPMC7240416
OpenAlexW3011416909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.