Evidence map›Paper›PMID 32326409›Full record

ArticleInternational journal of molecular sciences2020

Comparative Analysis of Functional and Structural Decline in Retinitis Pigmentosas.

Thiago Cabral, Jose Ronaldo Lima de Carvalho, Joonpyo Kim, Jin Kyun Oh, Sarah R Levi, Karen Sophia Park, Jimmy K Duong, Junhyung Park, Katherine Boudreault, Rubens Belfort and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Investigating Biomarkers forInternational journal of molecular sciences · 2022
    Article
  7. New criteria for evaluation of electroretinogram in patients with retinitis pigmentosa.Documenta ophthalmologica. Advances in ophthalmology · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Thiago CabralDepartment of Ophthalmology, Jonas Children's Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-1201-8772
Jose Ronaldo Lima de CarvalhoDepartment of Ophthalmology, Jonas Children's Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-7024-1702
Joonpyo KimDepartment of Statistics, Seoul National University, Seoul 08826, Korea.ORCID 0000-0003-0789-7685
Jin Kyun OhDepartment of Ophthalmology, Jonas Children's Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University, New York, NY 10032, USA.
Sarah R LeviDepartment of Ophthalmology, Jonas Children's Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-6503-1778
Karen Sophia ParkDepartment of Ophthalmology, Jonas Children's Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-1605-3110
Jimmy K DuongDepartment of Biostatistics, Columbia University, New York, NY 10032, USA.
Junhyung ParkDepartment of Statistics, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Katherine BoudreaultDepartment of Ophthalmology, Jonas Children's Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University, New York, NY 10032, USA.
Rubens BelfortDepartment of Ophthalmology, Federal University of São Paulo (UNIFESP), São Paulo, SP 04039-032, Brazil.
Stephen H TsangDepartment of Ophthalmology, Jonas Children's Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Columbia University, New York, NY 10032, USA.
Columbia University · USSeoul National University · KRState University of New York · USUniversidade Federal de Pernambuco · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Espírito Santo · BRUniversity of California, Los Angeles · US

Funding

Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
Toward mechanism- and gene-based therapies for retinal degenerationR01EY018213 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Stephen H Tsang · 2008 to 2026
$6.6M
Gene Silencing and Gene Editing in PhototransductionR01EY024698 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Stephen H Tsang · 2015 to 2026
$4.7M
Mechanistic Studies on Regenerative Medicine Approaches to Childhood BlindnessR01EY026682 · NEI · UNIVERSITY OF IOWA · PI BASSUK, ALEXANDER G, MAHAJAN, VINIT B · 2016 to 2019
$1.6M
Evaluating GWAS AMD Candidate Loci by Gene Editing in Human iPS CellsR21AG050437 · NIA · UNIVERSITY OF IOWA · PI BASSUK, ALEXANDER G, MAHAJAN, VINIT B · 2015 to 2016
$431k
Foundation Fighting Blindness TA-NMT-0116-0692-COLUNIH HHS P30EY019007NIH HHS R01EY018213NIH HHS R01EY024698NIH HHS R01EY026682NIH HHS R21AG050437
6 · The paper itself

Abstract

Retinitis pigmentosa (RP) is a category of inherited retinal dystrophies that is best prognosticated using electroretinography (ERG). In this retrospective cohort study of 25 patients with RP, we evaluated the correlation between 30 Hz flicker ERG and structural parameters in the retina. Internationally standardized 30 Hz flicker ERG recordings, short-wavelength autofluorescence (SW-AF), and spectral domain-optical coherence tomography (SD-OCT) were acquired at two visits at least one year apart. Vertical and horizontal hyperautofluorescent ring diameter measurements with SW-AF, as well as ellipsoid zone (EZ) line width measurements with SD-OCT, were used as structural parameters of disease progression. The 30 Hz flicker ERG amplitude decreased by 2.2 ± 0.8 µV/year (

Indexed as

AdolescentAdultAgedAged, 80 and overChildCohort StudiesDisease ProgressionElectroretinographyFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetinaRetinal DystrophiesERGinherited retinal dystrophyretinitis pigmentosa

Identifiers

PMID32326409
PMCPMC7215932
OpenAlexW3016726772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.