Evidence map›Paper›PMID 32326306›Full record

ArticleDiagnostics (Basel, Switzerland)2020

MicroRNA Expression Profile Changes after Cardiopulmonary Bypass and Ischemia/Reperfusion-Injury in a Porcine Model of Cardioplegic Arrest.

Attila Kiss, Stefan Heber, Anne-Margarethe Kramer, Matthias Hackl, Susanna Skalicky, Seth Hallström, Bruno K Podesser, David Santer

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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  8. HOxidative medicine and cellular longevity · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Attila KissLudwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-4652-1998
Stefan HeberInstitute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
Anne-Margarethe KramerLudwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research, Medical University of Vienna, 1090 Vienna, Austria.
Matthias HacklTAmiRNA GmbH, 1110 Vienna, Austria.
Susanna SkalickyTAmiRNA GmbH, 1110 Vienna, Austria.
Seth HallströmDivision of Physiological Chemistry, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.
Bruno K PodesserLudwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research, Medical University of Vienna, 1090 Vienna, Austria.
David SanterLudwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research, Medical University of Vienna, 1090 Vienna, Austria.
Medical University of Vienna · ATMedical University of Graz · ATUniversity Hospital of Basel · CH

Funding

Ludwig Boltzmann Society REM 2017-2020Medical Scientific Fund of the Mayor of the City of Vienna Foundation 17056
6 · The paper itself

Abstract

Identification of microRNAs (miRNA) associated with cardiopulmonary bypass, cardiac arrest and subsequent myocardial ischemia/reperfusion may unravel novel therapeutic targets and biomarkers. The primary aim of the present study was to investigate the effects of cardiopulmonary bypass and temperature of cardioplegic arrest on myocardial miRNA profile in pigs' left ventricular tissue. We employed next-generation sequencing to analyse miRNA profiles in the following groups: (1) hearts were arrested with antegrade warm St Thomas Hospital No. 2 (STH2) cardioplegia (

Indexed as

cardioprotectioncardiopulmonary bypassischemia/reperfusionmicroRNA

Identifiers

PMID32326306
PMCPMC7236010
OpenAlexW3020537437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.