ArticleBrain sciences2020
Transcranial Direct Current Stimulation at 4 mA Induces Greater Leg Muscle Fatigability in Women Compared to Men.
Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Effectiveness of transcranial direct current stimulation on balance and gait in patients with multiple sclerosis: systematic review and meta-analysis of randomized clinical trials.Journal of neuroengineering and rehabilitation · 2023Pooled it
- The influence of a single transcranial direct current stimulation session on physical fitness in healthy subjects: a systematic review.Experimental brain research · 2023Pooled it
- Sex Does Matter! The Influence of Sex on Outcomes of Transcranial Direct Current Stimulation (tDCS).Cells · 2026Review
- Fatigue and Physical Activity in People after COVID-19 in Poland.Journal of personalized medicine · 2023Article
- High Estrogen Levels Cause Greater Leg Muscle Fatigability in Eumenorrheic Young Women after 4 mA Transcranial Direct Current Stimulation.Brain sciences · 2022Article
- A pilot study of the moderating effect of gender on the physical activity and fatigue severity among recovered COVID-19 patients.PloS one · 2022Article
- Alterations in Leg Muscle Glucose Uptake and Inter-Limb Asymmetry after a Single Session of tDCS in Four People with Multiple Sclerosis.Brain sciences · 2021Article
- Personal Protective Equipment Alters Leg Muscle Fatigability Independent of Transcranial Direct Current Stimulation: A Comparison with Pre-COVID-19 Pandemic Results.Brain sciences · 2021Article
- Transcranial Direct Current Stimulation as a Treatment Tool for Mild Traumatic Brain Injury.Brain sciences · 2021Review
- Transcranial Direct Current Stimulation Enhances Muscle Strength of Non-dominant Knee in Healthy Young Males.Frontiers in physiology · 2021Article
- Post-COVID-19 Fatigue: Potential Contributing Factors.Brain sciences · 2020Article
- Different Effects of Transcranial Direct Current Stimulation on Leg Muscle Glucose Uptake Asymmetry in Two Women with Multiple Sclerosis.Brain sciences · 2020Article
- Sex difference in tDCS current mediated by changes in cortical anatomy: A study across young, middle and older adults.Brain stimulationArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcranial direct current stimulation (tDCS) has previously shown different cortical excitability and neuropsychological effects between women and men. However, the sex-specific effects of tDCS on leg muscle fatigability has not been investigated. The purpose of this study was to determine the effects of a single session of 2 mA and 4 mA primary motor cortex tDCS on leg muscle fatigability in healthy young men and women in a crossover design. Twenty participants (women = 10) completed isokinetic fatigue testing (40 maximal reps, 120°/s) of the knee extensors and flexors in conjunction with sham, 2 mA, and 4 mA tDCS in a double-blind, randomized design. The fatigue index from each condition was calculated. Women had significantly greater knee extensor fatigability in the 4 mA condition compared to men (57.8 ± 6.8% versus 44.1 ± 18.4%;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.