Evidence map›Paper›PMID 32326213›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Chromatographic Detection of 8-Hydroxy-2'-Deoxyguanosine in Leukocytes of Asbestos Exposed Workers for Assessing Past and Recent Carcinogen Exposures.

Filippo Cellai, Stefano Bonassi, Alfonso Cristaudo, Alessandra Bonotti, Monica Neri, Marcello Ceppi, Marco Bruzzone, Mirta Milić, Armelle Munnia, Marco Peluso

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Filippo CellaiCancer Risk Factor Branch, Regional Cancer Prevention Laboratory, ISPRO-Study, Prevention and Oncology Network Institute, 50139 Florence, Italy.
Stefano BonassiClinical and Molecular Epidemiology, IRCCS San Raffaele Pisana, 00166 Rome, Italy.ORCID 0000-0003-3833-6717
Alfonso CristaudoDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56010 Pisa, Italy.
Alessandra BonottiOccupational Medicine Unit, University of Pisa, 56010 Pisa, Italy.
Monica NeriClinical and Molecular Epidemiology, IRCCS San Raffaele Pisana, 00166 Rome, Italy.ORCID 0000-0003-4796-3675
Marcello CeppiUnit of Clinical Epidemiology, IRCCS Ospedale Policlinico San Martino, 16131 Genoa, Italy.
Marco BruzzoneUnit of Clinical Epidemiology, IRCCS Ospedale Policlinico San Martino, 16131 Genoa, Italy.ORCID 0000-0002-8821-4542
Mirta MilićMutagenesis Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Armelle MunniaCancer Risk Factor Branch, Regional Cancer Prevention Laboratory, ISPRO-Study, Prevention and Oncology Network Institute, 50139 Florence, Italy.
Marco PelusoCancer Risk Factor Branch, Regional Cancer Prevention Laboratory, ISPRO-Study, Prevention and Oncology Network Institute, 50139 Florence, Italy.ORCID 0000-0001-7646-7967

Funding

Istituto Nazionale per l'Assicurazione Contro Gli Infortuni sul Lavoro NARegione Toscana NA
6 · The paper itself

Abstract

Asbestos fibers include a group of silicate minerals that occur in the environment and are widely employed in occupational settings. Asbestos exposure has been associated to various chronic diseases; such as pulmonary fibrosis; mesothelioma; and lung cancer; often characterized by a long period of latency. Underlying mechanisms that are behind the carcinogenic effect of asbestos have not been fully clarified. Therefore; we have conducted an epidemiological study to evaluate the relationship between 8-hydroxy-2'-deoxyguanosine (8-oxodG), one of the most reliable biomarkers of oxidative stress and oxidative DNA damage; and asbestos exposure in the peripheral blood of residents in Tuscany and Liguria regions; Italy; stratified by occupational exposure to this carcinogen. Levels of 8-oxodG were expressed such as relative adduct labeling (RAL); the frequency of 8-oxodG per 10

Indexed as

8-oxodGasbestosleukocytes

Identifiers

PMID32326213
PMCPMC7235992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.