ArticleToxins2020
Liquid Chromatography Coupled to High-Resolution Mass Spectrometry for the Confirmation of Caribbean Ciguatoxin-1 as the Main Toxin Responsible for Ciguatera Poisoning Caused by Fish from European Atlantic Coasts.
Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Convergent Total Synthesis of Caribbean Ciguatoxin C-CTX1 and Its C3-Epimer.Journal of the American Chemical Society · 2026Article
- Comparison of LC-MS methods for the quantitation of ciguatoxins in fish - A collaborative study.Food chemistry: X · 2025Article
- Recent progress in the application of chromatography-coupled mass-spectrometry in the analysis of contaminants in food products.Food chemistry: X · 2025Article
- First Confirmed Occurrence of Ciguatera Poisoning in the UK from Imported Pinjalo Snapper (Marine drugs · 2025Article
- Isolation of Caribbean Ciguatoxin-5 (C-CTX5) and confirmation of its structure by NMR spectroscopy.Tetrahedron · 2024Article
- First Detection of Algal Caribbean Ciguatoxin in Amberjack Causing Ciguatera Poisoning in the Canary Islands (Spain).Toxins · 2024Article
- Article
- A 15-Year Retrospective Review of Ciguatera in the Madeira Islands (North-East Atlantic, Portugal).Toxins · 2023Review
- Review
- Article
- Identification of New CTX Analogues in Fish from the Madeira and Selvagens Archipelagos by Neuro-2a CBA and LC-HRMS.Marine drugs · 2022Article
- Current Trends and New Challenges in Marine Phycotoxins.Marine drugs · 2022Review
- Ciguatoxin Detection in Flesh and Liver of Relevant Fish Species from the Canary Islands.Toxins · 2022Article
- Extraction and LC-MS/MS Analysis of Ciguatoxins: A Semi-Targeted Approach Designed for Fish of Unknown Origin.Toxins · 2021Article
- Article
- Toxicity Screening of aMarine drugs · 2021Article
- Ciguatera Mini Review: 21st Century Environmental Challenges and the Interdisciplinary Research Efforts Rising to Meet Them.International journal of environmental research and public health · 2021Review
- Neurological Disturbances of Ciguatera Poisoning: Clinical Features and Pathophysiological Basis.Cells · 2020Review
- Advances in Detecting Ciguatoxins in Fish.Toxins · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Ciguatera poisoning (CP) is a common seafood intoxication mainly caused by the consumption of fish contaminated by ciguatoxins. Recent studies showed that Caribbean ciguatoxin-1 (C-CTX1) is the main toxin causing CP through fish caught in the Northeast Atlantic, e.g., Canary Islands (Spain) and Madeira (Portugal). The use of liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) combined with neuroblastoma cell assay (N2a) allowed the initial confirmation of the presence of C-CTX1 in contaminated fish samples from the abovementioned areas, nevertheless the lack of commercially available reference materials for these particular ciguatoxin (CTX) analogues has been a major limitation to progress research. The EuroCigua project allowed the preparation of C-CTX1 laboratory reference material (LRM) from fish species (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.