Evidence map›Paper›PMID 32326182›Full record

ReviewInternational journal of molecular sciences2020

Diabetic Cardiomyopathy and Ischemic Heart Disease: Prevention and Therapy by Exercise and Conditioning.

Antonio Crisafulli, Pasquale Pagliaro, Silvana Roberto, Lucia Cugusi, Giuseppe Mercuro, Antigone Lazou, Christophe Beauloye, Luc Bertrand, Derek J Hausenloy, Manuela Aragno and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

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  13. Chitosan Versus Dapagliflozin in a Diabetic Cardiomyopathy Mouse Model.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 6 countries.

Antonio CrisafulliDepartment of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Pasquale PagliaroDepartment of Clinical and Biological Science, University of Torino, 10043 Obassano (TO), Italy.ORCID 0000-0002-4386-1383
Silvana RobertoDepartment of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Lucia CugusiDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-7650-0640
Giuseppe MercuroDepartment of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Antigone LazouSchool of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-7889-9648
Christophe BeauloyePole of Cardiovascular Research, IREC Institute, UCLouvain, 1200 Brussels, Belgium.
Luc BertrandPole of Cardiovascular Research, IREC Institute, UCLouvain, 1200 Brussels, Belgium.ORCID 0000-0003-0655-7099
Derek J HausenloyCardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, Singapore 169857, Singapore.ORCID 0000-0003-0729-4956
Manuela AragnoDepartment of Clinical and Biological Science, University of Torino, 10043 Obassano (TO), Italy.ORCID 0000-0002-0453-5235
Claudia PennaDepartment of Clinical and Biological Science, University of Torino, 10043 Obassano (TO), Italy.
University of Cagliari · ITUniversity of Turin · ITAristotle University of Thessaloniki · GRAsia University · TWCliniques Universitaires Saint-Luc · BEUniversity of Sassari · IT

Funding

British Heart Foundation CS/14/3/31002Collaborative Centre Grant scheme NMRC/CGAug16C006COST Action EU-CARDIOPROTECTION CA16225Singapore Ministry of Education Academic Research Fund Tier 2 MOE2016-T2-2-021Singapore Ministry of Health's National Medical Research Council NMRC/CSA-SI/0011/2017
6 · The paper itself

Abstract

Metabolic syndrome, diabetes, and ischemic heart disease are among the leading causes of death and disability in Western countries. Diabetic cardiomyopathy is responsible for the most severe signs and symptoms. An important strategy for reducing the incidence of cardiovascular disease is regular exercise. Remote ischemic conditioning has some similarity with exercise and can be induced by short periods of ischemia and reperfusion of a limb, and it can be performed in people who cannot exercise. There is abundant evidence that exercise is beneficial in diabetes and ischemic heart disease, but there is a need to elucidate the specific cardiovascular effects of emerging and unconventional forms of exercise in people with diabetes. In addition, remote ischemic conditioning may be considered among the options to induce beneficial effects in these patients. The characteristics and interactions of diabetes and ischemic heart disease, and the known effects of exercise and remote ischemic conditioning in the presence of metabolic syndrome and diabetes, are analyzed in this brief review.

Indexed as

ExerciseIschemic PreconditioningAnimalsDiabetes MellitusDiabetic CardiomyopathiesDisease ManagementDisease SusceptibilityHumansMetabolic Networks and PathwaysMyocardial IschemiaMyocardial Reperfusion Injurydiabetic cardiomyopathyexercisehyperglycemiaischemia/reperfusion injurymetabolismmitochondriaremote conditioning

Identifiers

PMID32326182
PMCPMC7215312
OpenAlexW3012329805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.