Evidence map›Paper›PMID 32326075›Full record

ReviewInternational journal of molecular sciences2020

Rosanna Mattossovich, Rosa Merlo, Riccardo Miggiano, Anna Valenti, Giuseppe Perugino

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. First thermostable CLIP-Computational and structural biotechnology journal · 2022
    Article
  6. Article
  7. Characterization of the Proteins Involved in the DNA Repair Mechanism inInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rosanna MattossovichInstitute of Bioscience and BioResources, National Research Council of Italy, Via Pietro Castellino 111, 80131 Naples, Italy.
Rosa MerloInstitute of Bioscience and BioResources, National Research Council of Italy, Via Pietro Castellino 111, 80131 Naples, Italy.
Riccardo MiggianoDepartment of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Anna ValentiInstitute of Bioscience and BioResources, National Research Council of Italy, Via Pietro Castellino 111, 80131 Naples, Italy.
Giuseppe PeruginoInstitute of Bioscience and BioResources, National Research Council of Italy, Via Pietro Castellino 111, 80131 Naples, Italy.
Institute of Biosciences and Bioresources · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome of living cells is continuously exposed to endogenous and exogenous attacks, and this is particularly amplified at high temperatures. Alkylating agents cause DNA damage, leading to mutations and cell death; for this reason, they also play a central role in chemotherapy treatments. A class of enzymes known as AGTs (alkylguanine-DNA-alkyltransferases) protects the DNA from mutations caused by alkylating agents, in particular in the recognition and repair of alkylated guanines in

Indexed as

DNA RepairAlkylationBiotechnologyDNA DamageDNA ReplicationMolecular Targeted TherapyNeoplasmsO(6)-Methylguanine-DNA MethyltransferaseStructure-Activity RelationshipThermodynamicsThermoproteusO(6)-Methylguanine-DNA MethyltransferaseAGTalkylation damagebiotechnological toolsDNA repairthermophilic sources

Identifiers

PMID32326075
PMCPMC7216122
OpenAlexW3017043401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.