Evidence map›Paper›PMID 32325834›Full record

ArticlePharmaceutics2020

Carminic Acid Linked to Silica Nanoparticles as Pigment/Antioxidant Bifunctional Excipient for Pharmaceutical Emulsions.

Francisco Arriagada, Catalina Ugarte, Germán Günther, María Angélica Larraín, Víctor Guarnizo-Herrero, Santi Nonell, Javier Morales

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Francisco ArriagadaInstituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, 5110033 Valdivia, Chile.ORCID 0000-0001-8404-6492
Catalina UgarteFacultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 8380494 Santiago, Chile.
Germán GüntherFacultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 8380494 Santiago, Chile.ORCID 0000-0002-4733-8426
María Angélica LarraínFacultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 8380494 Santiago, Chile.ORCID 0000-0001-6433-194X
Víctor Guarnizo-HerreroFacultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Santi NonellInstitut Químic de Sarrià (IQS), Universidad Ramon Llull. Via Augusta 390, 08017 Barcelona, Spain.ORCID 0000-0002-8900-5291
Javier MoralesFacultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, 8380494 Santiago, Chile.
University of Chile · CLAustral University of Chile · CLInstitut Químic de Sarrià · ESUniversidad Complutense de Madrid · ES

Funding

Comisión Nacional de Investigación Científica y Tecnológica 21160932Fondo Nacional de Desarrollo Científico y Tecnológico 1160757Ministerio de Economía, Industria y Competitividad, Gobierno de España CTQ2016-78454-C2-1-RUniversidad de Chile PII2019
6 · The paper itself

Abstract

The incorporation of pigments and natural polyphenols into inorganic matrices, resulting in a hybrid material that improves the resistance and chemical stability of the pigments and the antioxidant capacity of the materials, has been of great interest to the pharmaceutical, chemical and food industries. The aim of this work was to prepare and characterize a bifunctional pigment-antioxidant nanomaterial-based carminic acid-decorated solid core-mesoporous shell silica nanoparticles, evaluating its properties as a pigment, its antioxidant capacity and its properties as a chemical stabilizer of emulsions. The chemical stability of oil-in-water (O/W) Pickering emulsions was evaluated determining the stability of vitamin E solubilized in the oil phase. Carminic acid was attached through the action of coupling ethylcarbodiimide hydrochloride (EDC)/

Indexed as

antioxidantcarminic acidemulsionnanoexcipientssilica nanoparticles

Identifiers

PMID32325834
PMCPMC7238007
OpenAlexW3016541331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.