Evidence map›Paper›PMID 32325745›Full record

ArticleJournal of clinical medicine2020

Efficacy and Safety of a Novel Submucosal Injection Solution for Resection of Gastrointestinal Lesions.

Cristina Moles-Aranda, Raquel González-Pérez, Francisco Javier Gallego-Rojo, Olga Martínez-Augustin, Beatriz Clares-Naveros, Fermín Sánchez de Medina, José Antonio Morales-Molina

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cristina Moles-ArandaDepartment of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Granada, Campus Universitario de Cartuja, 18071 Granada, Spain.
Raquel González-PérezDepartment of Pharmacology, CIBERehd, Instituto de Investigación Biosanitaria ibs.GRANADA, School of Pharmacy, University of Granada, Campus Universitario de Cartuja, 18071 Granada, Spain.ORCID 0000-0002-7956-9763
Francisco Javier Gallego-RojoDepartment of Digestive, Hospital de Poniente, Ctra. Almerimar, 04700 El Ejido, Almería, Spain.
Olga Martínez-AugustinInstituto de Investigación Biosanitaria ibs.GRANADA, University of Granada, 18071 Granada, Spain.
Beatriz Clares-NaverosDepartment of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Granada, Campus Universitario de Cartuja, 18071 Granada, Spain.ORCID 0000-0001-6126-7890
Fermín Sánchez de MedinaDepartment of Pharmacology, CIBERehd, Instituto de Investigación Biosanitaria ibs.GRANADA, School of Pharmacy, University of Granada, Campus Universitario de Cartuja, 18071 Granada, Spain.ORCID 0000-0002-4516-5824
José Antonio Morales-MolinaInstituto de Investigación Biosanitaria ibs.GRANADA, University of Granada, 18071 Granada, Spain.
Universidad de Granada · ESHospital de Poniente · ES

Funding

Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía CTS164, CTS235, CTS676Instituto de Salud Carlos III -Junta de Andalucía, Consejería de Salud PIN-0479-2016Ministerio de Economía y Competitividad SAF2017-88457-R, AGL2017-85270-RNakafarma S.L. -
6 · The paper itself

Abstract

Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are minimally invasive and efficient techniques for the removal of gastrointestinal (GI) mucosal polyps. In both techniques, submucosal injection solutions are necessary for complete effectiveness and safety during the intervention to be obtained. The main objective of this study was to evaluate the efficacy and safety of a new sterile submucosal injection solution for EMR/ESD used within a clinical protocol in patients with intestinal polyps. We carried out a prospective study between 2016 and 2017 with patients who attended the Endoscopy Consultation-Digestive Department of Primary Hospital. Patients were selected for EMR/ESD after the application of clinical protocols. Thirty-six patients were selected (≥ 66 years with comorbidities and risk factors). Lesions were located mainly in the colon. Our solution presented an intestinal lift ≥ 60 min in EMR/ESD and a high expansion of tissue, optimum viscosity, and subsequent complete resorption. The genes

Indexed as

efficacyendoscopic mucosal resectionendoscopic submucosal dissectiongastrointestinal endoscopysafetysubmucosal injection

Identifiers

PMID32325745
PMCPMC7230585
OpenAlexW3016549999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.