Evidence map›Paper›PMID 32325715›Full record

ArticleCancers2020

Dexamethasone Attenuates X-Ray-Induced Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle in Breast Tissue and Subsequent Breast Fibrosis.

Guanmin Meng, Melinda Wuest, Xiaoyun Tang, Jennifer Dufour, Todd P W McMullen, Frank Wuest, David Murray, David N Brindley

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Genetic Polymorphisms ofInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Guanmin MengDepartment of Biochemistry, University of Alberta, Edmonton, AB T6G 2S2, Canada.
Melinda WuestCancer Research Institute of Northern Alberta, University of Alberta, Edmonton, AB T6G 2S2, Canada.
Xiaoyun TangDepartment of Biochemistry, University of Alberta, Edmonton, AB T6G 2S2, Canada.
Jennifer DufourDepartment of Oncology, Division of Oncologic Imaging, University of Alberta, Edmonton, AB T6G 2R7, Canada.
Todd P W McMullenCancer Research Institute of Northern Alberta, University of Alberta, Edmonton, AB T6G 2S2, Canada.
Frank WuestCancer Research Institute of Northern Alberta, University of Alberta, Edmonton, AB T6G 2S2, Canada.
David MurrayCancer Research Institute of Northern Alberta, University of Alberta, Edmonton, AB T6G 2S2, Canada.
David N BrindleyDepartment of Biochemistry, University of Alberta, Edmonton, AB T6G 2S2, Canada.ORCID 0000-0003-2227-0020
University of Alberta · CA

Funding

Canadian Cancer Society Research Institute 703926
6 · The paper itself

Abstract

We recently showed that radiation-induced DNA damage in breast adipose tissue increases autotaxin secretion, production of lysophosphatidate (LPA) and expression of LPA

Indexed as

adipocytesadipose tissuebreast cancerchemokinescytokinesvasculitis

Identifiers

PMID32325715
PMCPMC7226295
OpenAlexW3016688597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.