Evidence map›Paper›PMID 32325648›Full record

ArticleMetabolites2020

Comparative Evaluation of Data Dependent and Data Independent Acquisition Workflows Implemented on an Orbitrap Fusion for Untargeted Metabolomics.

Pierre Barbier Saint Hilaire, Kathleen Rousseau, Alexandre Seyer, Sylvain Dechaumet, Annelaure Damont, Christophe Junot, François Fenaille

Abstract read
In one paragraph

Article in Metabolites, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Metabolomics of Chinese Hamster Ovary Cells.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Journal of pharmaceutical analysis · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pierre Barbier Saint HilaireDépartement Médicaments et Technologies pour la Santé (DMTS), CEA, INRAE, Université Paris-Saclay, MetaboHUB, F-91191 Gif sur Yvette, France.
Kathleen RousseauDépartement Médicaments et Technologies pour la Santé (DMTS), CEA, INRAE, Université Paris-Saclay, MetaboHUB, F-91191 Gif sur Yvette, France.
Alexandre SeyerMedDay Pharmaceuticals SA, 24 Rue de la Pépinière, F-75008 Paris, France.
Sylvain DechaumetMedDay Pharmaceuticals SA, 24 Rue de la Pépinière, F-75008 Paris, France.ORCID 0000-0002-3387-7250
Annelaure DamontDépartement Médicaments et Technologies pour la Santé (DMTS), CEA, INRAE, Université Paris-Saclay, MetaboHUB, F-91191 Gif sur Yvette, France.ORCID 0000-0003-4075-5187
Christophe JunotDépartement Médicaments et Technologies pour la Santé (DMTS), CEA, INRAE, Université Paris-Saclay, MetaboHUB, F-91191 Gif sur Yvette, France.
François FenailleDépartement Médicaments et Technologies pour la Santé (DMTS), CEA, INRAE, Université Paris-Saclay, MetaboHUB, F-91191 Gif sur Yvette, France.ORCID 0000-0001-6787-4149

Funding

Agence Nationale de la Recherche ANR-11-INBS-0010
6 · The paper itself

Abstract

Constant improvements to the Orbitrap mass analyzer, such as acquisition speed, resolution, dynamic range and sensitivity have strengthened its value for the large-scale identification and quantification of metabolites in complex biological matrices. Here, we report the development and optimization of Data Dependent Acquisition (DDA) and Sequential Window Acquisition of all THeoretical fragment ions (SWATH-type) Data Independent Acquisition (DIA) workflows on a high-field Orbitrap Fusion

Indexed as

DDADIAhigh resolution mass spectrometrymetabolomicsOrbitrap Fusion

Identifiers

PMID32325648
PMCPMC7240956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.