Evidence map›Paper›PMID 32325642›Full record

ArticleInternational journal of molecular sciences2020

A Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2.

Renfei Lu, Xiuming Wu, Zhenzhou Wan, Yingxue Li, Xia Jin, Chiyu Zhang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Portable RT-LAMP Platform for Rapid Point-of-Care Detection for SFTSV.Journal of microbiology and biotechnology · 2025
    Article
  9. Standardization and performance of SARS-CoV-2 RT-LAMP detection: a reliable, inexpensive, and alternative diagnostic assay.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Development of a Novel Nested-RT-LAMP Assay for the Rapid and Accurate Coronavirus Disease-2019 Diagnosis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Renfei LuClinical Laboratory, Nantong Third Hospital Affiliated to Nantong University, Nantong 226006, China.
Xiuming WuPathogen Discovery and Evolution Unit, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China.
Zhenzhou WanMedical Laboratory of Taizhou Fourth People's Hospital, Taizhou 225300 China.
Yingxue LiPathogen Discovery and Evolution Unit, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China.
Xia JinShanghai Public Health Clinical Center, Fudan University, Jinshan District, Shanghai 201508, China.
Chiyu ZhangPathogen Discovery and Evolution Unit, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China.ORCID 0000-0001-8735-9857

Funding

National Science and Technology Major Project of China 2019YFC1200603 and 2017ZX10103009-002Natural Science Research Project of Nantong Science and Technology Bureau MS12019048
6 · The paper itself

Abstract

COVID-19 has become a major global public health burden, currently causing a rapidly growing number of infections and significant morbidity and mortality around the world. Early detection with fast and sensitive assays and timely intervention are crucial for interrupting the spread of the COVID-19 virus (SARS-CoV-2). Using a mismatch-tolerant amplification technique, we developed a simple, rapid, sensitive and visual reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for SARS-CoV-2 detection based on its

Indexed as

Coronavirus InfectionsPandemicsPneumonia, ViralBetacoronavirusBiological AssayClinical Laboratory TechniquesCOVID-19COVID-19 TestingHumansNucleic Acid Amplification TechniquesReverse Transcriptase Polymerase Chain ReactionReverse TranscriptionSARS-CoV-2Sensitivity and SpecificityCOVID-19LAMPpneumoniaPOCTSARS-CoV-2

Identifiers

PMID32325642
PMCPMC7216271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.